health and disease

Significant interest in recent years has focused on gut microbiota-host interaction because accumulating evidence has revealed… (More)

The central nervous system (CNS) and its meningeal coverings accommodate a diverse myeloid compartment that includes parenchymal… (More)

Aside from inheriting half of the genome of each of our parents, we are born with a small number of novel mutations that occurred… (More)

Gut microbiota is the community of live microorganisms residing in the digestive tract. There are many groups of researchers… (More)

Interest in the role of the microbiome in human health has burgeoned over the past decade with the advent of new technologies for… (More)

Microglia — resident myeloid-lineage cells in the brain and the spinal cord parenchyma — function in the maintenance of normal… (More)

Epigenetics is one of the most rapidly expanding fields in biology. The recent characterization of a human DNA methylome at… (More)

l-Arginine (Arg) is synthesised from glutamine, glutamate, and proline via the intestinal-renal axis in humans and most other… (More)

Blood vessels constitute the first organ in the embryo and form the largest network in our body but, sadly, are also often deadly… (More)

According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain… (More)