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halomethylketone pyrrolopyrimidine-cmk

National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Heterocyclic Compounds, 2-Ring

Papers overview

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2019
2019
Designing a chemical inhibitor of the AAA protein spastin using active site mutations
Spastin is a microtubule-severing AAA (ATPases associated with diverse cellular activities) protein needed for cell division and… Expand
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2018
2018
Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human &ggr;&dgr;T cells against colon cancer
Abstract &ggr;&dgr;T cells are a distinct T‐cell subset that display unique characteristics regarding T‐cell receptor gene usage… Expand
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2013
2013
Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors.
The synthesis and biological evaluation of novel Tie-2 kinase inhibitors are presented. Based on the pyrrolopyrimidine chemotype… Expand
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2012
2012
Stimulation of Wnt/ß-Catenin Pathway in Human CD8+ T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype
Cancer can be treated by adoptive cell transfer (ACT) of T lymphocytes. However, how to optimally raise human T cells to a… Expand
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1997
1997
Neuroprotective properties of a novel antioxidant (U-101033E) with improved blood-brain barrier permeability in focal cerebral ischemia.
Many efforts have been undertaken to develop antioxidants against free radical induced brain damage, 21-aminosteroids, although… Expand
1997
1997
The pretransition of dipalmitoyllecithin bilayers as probed by the fluorescent pyrrolopyrimidine, U-104067.
The amphiphilic pyrrolopyrimidine, U-104067, is a fluorophore ideally suited to report on the relative hydrophobicities of… Expand
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