hSWI/SNF

Known as: Human SWI/SNF 
hSWI/SNF is an ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis. The… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
024619942017

Papers overview

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Highly Cited
2004
Highly Cited
2004
Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their role in… (More)
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Highly Cited
2000
Highly Cited
2000
We present evidence that Rb forms a repressor containing histone deacetylase (HDAC) and the hSWI/SNF nucleosome remodeling… (More)
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Highly Cited
2000
Highly Cited
2000
Germline mutations in the tumor suppressor gene, BRCA1, predispose individuals to breast and ovarian cancers. Using a combination… (More)
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Highly Cited
2000
Highly Cited
2000
The ordered assembly of immunoglobulin and TCR genes by V(D)J recombination depends on the regulated accessibility of individual… (More)
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Highly Cited
2000
Highly Cited
2000
The SWI/SNF family of chromatin-remodeling complexes facilitates gene activation by assisting transcription machinery to gain… (More)
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Highly Cited
1999
Highly Cited
1999
Protein complexes of the SWI/SNF family remodel nucleosome structure in an ATP-dependent manner. Each complex contains between 8… (More)
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Highly Cited
1998
Highly Cited
1998
During mitosis, chromatin is condensed into mitotic chromosomes and transcription is inhibited, processes that might be opposed… (More)
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Highly Cited
1998
Highly Cited
1998
The human SWI/SNF complex remodels nucleosome structure in an ATP-dependent manner, although the nature of this change has not… (More)
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Highly Cited
1994
Highly Cited
1994
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by blocking access of sequence… (More)
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Highly Cited
1994
Highly Cited
1994
BINDING of the TATA-binding protein (TBP) to the TATA box is required for transcription from many eukaryotic promoters in gene… (More)
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