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hSWI/SNF

Known as: Human SWI/SNF 
hSWI/SNF is an ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis. The… Expand
National Institutes of Health

Related topics

Related topics

7 relations
AT-Rich Interactive Domain-Containing Protein 1BE-RC1SMARCA2 protein, humanSMARCB1 protein, human
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Papers overview

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Highly Cited
2004
Highly Cited
2004
Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.
Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their role in… Expand
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2003
2003
Linker histone H1 modulates nucleosome remodeling by human SWI/SNF.
Chromatin, a combination of nucleosomes and linker histones, inhibits transcription by blocking polymerase movement and access of… Expand
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2001
2001
Direct imaging of human SWI/SNF-remodeled mono- and polynucleosomes by atomic force microscopy employing carbon nanotube tips.
Chromatin-remodeling complexes alter chromatin structure to facilitate, or in some cases repress, gene expression. Recent studies… Expand
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Highly Cited
2000
Highly Cited
2000
Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
We present evidence that Rb forms a repressor containing histone deacetylase (HDAC) and the hSWI/SNF nucleosome remodeling… Expand
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Highly Cited
2000
Highly Cited
2000
Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA.
The ordered assembly of immunoglobulin and TCR genes by V(D)J recombination depends on the regulated accessibility of individual… Expand
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2000
2000
Human SWI/SNF nucleosome remodeling activity is partially inhibited by linker histone H1.
The physical structure and the compact nature of the eukaryotic genome present a functional barrier for any cellular process that… Expand
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Highly Cited
1998
Highly Cited
1998
Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State
The human SWI/SNF complex remodels nucleosome structure in an ATP-dependent manner, although the nature of this change has not… Expand
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Highly Cited
1998
Highly Cited
1998
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.
During mitosis, chromatin is condensed into mitotic chromosomes and transcription is inhibited, processes that might be opposed… Expand
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Highly Cited
1997
Highly Cited
1997
Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix
Biochemical and genetic evidence suggest that the SWI/SNF complex is involved in the remodeling of chromatin during gene… Expand
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Highly Cited
1994
Highly Cited
1994
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by blocking access of sequence… Expand
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