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hSWI/SNF

Known as: Human SWI/SNF 
hSWI/SNF is an ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis. The… Expand
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their role in… Expand
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2003
2003
Chromatin, a combination of nucleosomes and linker histones, inhibits transcription by blocking polymerase movement and access of… Expand
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2001
2001
Chromatin-remodeling complexes alter chromatin structure to facilitate, or in some cases repress, gene expression. Recent studies… Expand
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Highly Cited
2000
Highly Cited
2000
We present evidence that Rb forms a repressor containing histone deacetylase (HDAC) and the hSWI/SNF nucleosome remodeling… Expand
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Highly Cited
2000
Highly Cited
2000
The ordered assembly of immunoglobulin and TCR genes by V(D)J recombination depends on the regulated accessibility of individual… Expand
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2000
2000
The physical structure and the compact nature of the eukaryotic genome present a functional barrier for any cellular process that… Expand
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Highly Cited
1998
Highly Cited
1998
The human SWI/SNF complex remodels nucleosome structure in an ATP-dependent manner, although the nature of this change has not… Expand
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Highly Cited
1998
Highly Cited
1998
During mitosis, chromatin is condensed into mitotic chromosomes and transcription is inhibited, processes that might be opposed… Expand
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Highly Cited
1997
Highly Cited
1997
Biochemical and genetic evidence suggest that the SWI/SNF complex is involved in the remodeling of chromatin during gene… Expand
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Highly Cited
1994
Highly Cited
1994
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by blocking access of sequence… Expand
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