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guanosine tetraphosphate biosynthetic process

Known as: guanosine tetraphosphate anabolism, guanosine tetraphosphate biosynthesis, guanosine tetraphosphate formation 
The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
RATIONALE Premature termination codons (PTCs) in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic… Expand
2016
2016
Currently approved platelet adenosine diphosphate (ADP) receptor antagonists target only the platelet P2Y12 receptor. Moreover… Expand
2007
2007
Tryptophanyl-tRNA synthetase (TrpRS) is a functionally dimeric ligase, which specifically couples hydrolysis of ATP to AMP and… Expand
Highly Cited
2002
Highly Cited
2002
The crystal structure of C. elegans Ap(4)A hydrolase has been determined for the free enzyme and a binary complex at 2.0 A and 1… Expand
Highly Cited
2001
Highly Cited
2001
The selectivities of the diadenosine polyphosphates (Ap(n)As, n=2-6) at the human P2Y(1), P2Y(2), P2Y(4), P2Y(6) and P2Y(11… Expand
1999
1999
The six-step synthesis of the di-triethylammonium salt of 5[prime]-O -trityl-6-N-pivaloyladenosine-2[prime]-(H -phosphonate)-3… Expand
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Highly Cited
1991
Highly Cited
1991
The dinucleotide AppppA (5′,5′″‐P1, P4‐diadenosine tetraphosphate) is rapidly synthesized in cells exposed to heat stress or… Expand
Highly Cited
1989
Highly Cited
1989
The role of aminoacyl-tRNA synthetases in the in vivo synthesis of adenylylated bis(5'-nucleosidyl) tetraphosphates (Ap4N) was… Expand
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1985
1985
A clone overproducing diadenosine tetraphosphatase (diadenosine 5', 5'''-P1, P4-tetraphosphate pyrophosphohydrolase) activity was… Expand
Highly Cited
1968
Highly Cited
1968
Abstract Analysis of the acid-soluble fraction during growth and development of the brine shrimp, Artemia salina , using… Expand