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growth factor receptor-bound protein 2

Known as: Abundant Src Homology Protein, GRB2 Adaptor Protein, Growth Factor Receptor Bound Protein 2 
GRB2 forms a complex with activated EGFR and the RAS-specific guanine nucleotide exchange factor SOS1, thereby mediating the growth factor-induced… 
National Institutes of Health

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Adaptor Signaling Protein GeneAngiotensin II Signaling PathwayB Cell Receptor Signaling PathwayEGF Signaling Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Overexpression of GRB 2 is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma
The adapter protein growth factor receptor-bound 2 (GRB2) is essential for various basic cellular functions by mediating the… 
Review
2011
Review
2011
GAB2 (GRB2-associated binding protein 2)
Review on GAB2 (GRB2-associated binding protein 2), with data on DNA, on the protein encoded, and where the gene is implicated. 
2011
2011
GRB 2 couples RhoU to epidermal growth factor receptor signaling and cell migration
This article was published online ahead of print in MBoC in Press (http://www .molbiolcell.org/cgi/doi/10.1091/mbc.E10-12-0969… 
2010
2010
A study on growth factor receptor protein binding protein 2 GRB2 and APP intracellular C terminal domain AICD trafficking in relation to alzheimers disease pathogenesis
2009
2009
P-72: Insulin-induced activation of MAP kinase involves GRB-2, SHPTP2, PI-3 kinase and PLCγ
Treatment of cells with insulin results in activation of signal transduction pathways involved in metabolic as well as mitogenic… 
2008
2008
Effect of inhibiting expression of growth factor receptor-bound protein-2 on proliferation of breast cancer cells
AIM To confirm the effect of growth factor receptor-bound protein-2(Grb2)inhibition on the advance of breast cancer.METHODS Grb2… 
2003
2003
The Adapter Protein GRB2 Is Required for Neointima Formation in Response to Vascular Injury
2002
2002
Investigation of the GRB 2 , GRB 7 , and CSH 1 genes as candidates for the Silver-Russell syndrome ( SRS ) on chromosome 17 q
Silver-Russell syndrome (SRS) (MIM 180860) is characterised by intrauterine and postnatal growth restriction, in association with… 
2002
2002
Tau binds to phosphatidylinositol-3-kinase, GRB2 phospholipase C gamma-1 and SRC-family kinases through SH3 domain
1995
1995
Ash/Grb2 - その多様なシグナル産生メカニズムの解明に向けて -