granulomatous inflammation
National Institutes of Health
Papers overview
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RATIONALE
The critical innate immune mechanisms that regulate granulomatous inflammation in sarcoidosis are unknown. Because the…
Transmembrane TNF-α, a precursor of the soluble form of TNF-α, is expressed on activated macrophages and lymphocytes as well as…
Mutations in the NOD2 gene are strong genetic risk factors for ileal Crohn’s disease. However, the mechanism by which these…
BACKGROUND
Tumor necrosis factor (TNF)-alpha is produced by macrophages and other cells, and is believed to participate in…
Osteopontin (Opn) is a secreted adhesive, glycosylated phosphoprotein that contains the arginine‐glycine‐aspartic acid (RGD) cell…
Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory lesion of the breast clinically simulating carcinoma. The…
Recent advances in cellular and molecular biology have provided important new avenues to assess mechanisms of granuloma formation…
The granulomatous inflammatory response is a special type of chronic inflammation characterised by often focal collections of…