graft versus tumor induction

Known as: Graft-Versus-Tumor Induction, graft versus host disease induction, graft-versus-tumor 
An immune response that involves a reaction by immune cells that are present in transplanted tissue, such as bone marrow or peripheral blood, to a… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
PURPOSE The graft-versus-tumor (GVT) effect is a potent form of immunotherapy against many hematologic malignancies and some… (More)
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Highly Cited
2004
Highly Cited
2004
Graft-versus-host disease (GVHD) represents a major hurdle impeding the efficacy of allogeneic bone marrow transplantation (BMT… (More)
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Highly Cited
2004
Highly Cited
2004
We have developed a mouse system by which to track the migration and homing of cells in a setting of bone marrow transplantation… (More)
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Highly Cited
2003
Highly Cited
2003
Mature donor T cells cause graft-versus-host disease (GVHD), but they are also the main mediators of the beneficial graft-versus… (More)
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Highly Cited
2003
Highly Cited
2003
CD4+CD25+ regulatory T cells (Treg's) play a pivotal role in preventing organ-specific autoimmune diseases and in inducing… (More)
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Highly Cited
2002
Highly Cited
2002
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that exhibits specific… (More)
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Highly Cited
2002
Highly Cited
2002
In mice, donor leukocyte infusion (DLI) given to established mixed allogeneic chimeras can mediate powerful graft-versus-host… (More)
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Highly Cited
2001
Highly Cited
2001
Toxicities have limited the use of allogeneic hematopoietic cell transplantation (HCT) to younger, medically fit patients. In a… (More)
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Highly Cited
1998
Highly Cited
1998
Bone marrow transplantation (BMT) is currently used for the treatment of a variety of neoplastic diseases. However, significant… (More)
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Highly Cited
1997
Highly Cited
1997
Donor lymphocyte infusions, by virtue of a graft-versus-tumor effect, have been shown to induce remissions in leukemia that… (More)
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