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glycosphingolipid biosynthetic process

Known as: glycosphingolipid biosynthesis, glycosphingolipid anabolism, glycosphingolipid synthesis 
The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Background— Glycosphingolipids, integral components of the cell membrane, have been shown to serve as messengers, transducing… Expand
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Highly Cited
2009
Highly Cited
2009
Adipose tissue is a critical mediator in obesity-induced insulin resistance. Previously we have demonstrated that pharmacological… Expand
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Highly Cited
2007
Highly Cited
2007
Previous reports have shown that glycosphingolipids can modulate the activity of the insulin receptor, and studies in transgenic… Expand
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Highly Cited
2007
Highly Cited
2007
Glycosphingolipids are controlled by the spatial organization of their metabolism and by transport specificity. Using… Expand
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Highly Cited
2005
Highly Cited
2005
The Drosophila genes, brainiac and egghead, encode glycosyltransferases predicted to act sequentially in early steps of… Expand
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Highly Cited
2004
Highly Cited
2004
Transfection studies have implicated the multiple drug resistance pump, MDR1, as a glucosyl ceramide translocase within the Golgi… Expand
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Review
2000
Review
2000
  • T. Yamashita
  • Seikagaku. The Journal of Japanese Biochemical…
  • 2000
  • Corpus ID: 12664844
Glycosphingolipids (GSLs) are believed to be integral for the dynamics of many cell membrane events, including cellular… Expand
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Highly Cited
1998
Highly Cited
1998
Biosynthesis of plasma membrane sphingolipids involves the coordinate action of enzymes localized to individual compartments of… Expand
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Highly Cited
1996
Highly Cited
1996
We have isolated a cDNA encoding human ceramide glucosyltransferase (glucosylceramide synthase, UDP-glucose:N-acylsphingosine D… Expand
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Highly Cited
1996
Highly Cited
1996
Glucosylceramide (GlcCer) is synthesized at the cytosolic surface of the Golgi complex while enzymes acting in late steps of… Expand
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