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glycoprotein 6-alpha-L-fucosyltransferase activity

Known as: FucT, GDPfucose-glycoprotein fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity 
Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
A common argument against using plants as a production system for therapeutic proteins is their inability to perform authentic… Expand
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Review
2003
Review
2003
MPL (Corixa) adjuvant is a chemically modified derivative of lipopolysaccharide that displays greatly reduced toxicity while… Expand
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2003
2003
It has been established that sialyl Lewis x in core 2 branched O-glycans serves as an E- and P-selectin ligand. Recently, it was… Expand
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Highly Cited
2001
Highly Cited
2001
E-, P-, and L-selectin counterreceptor activities, leukocyte trafficking, and lymphocyte homing are controlled prominently but… Expand
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2001
2001
A role for Stat4 in IL-12-induced up-regulation of selectin ligands on Th1 cells was explored. Th1 cells generated from Stat4… Expand
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Highly Cited
2000
Highly Cited
2000
Noninflamed skin venules support constitutive leukocyte rolling. P-selectin controls the rolling frequency, whereas E-selectin… Expand
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Highly Cited
1998
Highly Cited
1998
The alpha1,3-fucosyltransferase, FucT-VII, is crucial for the formation of ligands for all three selectins, and its expression… Expand
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Highly Cited
1998
Highly Cited
1998
The selectins are membrane glycoproteins promoting adhesive events between leukocytes, platelets, and endothelial cells. We have… Expand
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1997
1997
E-selectin is a carbohydrate-binding endothelial cell adhesion molecule that reportedly interacts with several related sialylated… Expand
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Highly Cited
1996
Highly Cited
1996
Selectin-ligands on T cells contribute to the recruitment of circulating cells into chronic inflammatory lesions in the skin and… Expand
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