glutathione peroxidase 1

Known as: Cellular Glutathione Peroxidase, GPX1 Protein, EC 1.11.1.9 
Glutathione peroxidase 1 (203 aa, ~22 kDa) is encoded by the human GPX1 gene. This protein plays a role in glutathione metabolism, peroxide reduction… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
020406019902018

Papers overview

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2010
2010
Genetic factors can contribute to autistic disorder (AD). Abnormal genes of oxidative stress pathways and increased oxidative… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES This study examined the association between genetic polymorphisms and enzyme activity for antioxidant enzymes that… (More)
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2004
2004
PURPOSE The glutathione peroxidase 1 gene (GPX1) and the manganese superoxide dismutase gene (MnSOD) encode the main antioxidant… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Cellular antioxidant enzymes such as glutathione peroxidase 1 and superoxide dismutase have a central role in the… (More)
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Highly Cited
2003
Highly Cited
2003
A role for allelic variation within the gene for the antioxidant selenoprotein glutathione peroxidase 1 (GPx-1) in the risk or… (More)
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2002
2002
OBJECTIVE We tested the hypothesis that deficiency of cellular glutathione peroxidase (GPx-1) enhances susceptibility to… (More)
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Highly Cited
2002
Highly Cited
2002
Cellular glutathione peroxidase (GPx-1) is the most abundant intracellular isoform of the GPx antioxidant enzyme family. In this… (More)
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Highly Cited
2000
Highly Cited
2000
Human cellular glutathione peroxidase 1 (hGPX1) is a selenium-dependent enzyme that participates in the detoxification of… (More)
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Highly Cited
1997
Highly Cited
1997
Glutathione peroxidase, a selenium-containing enzyme, is believed to protect cells from the toxicity of hydroperoxides. The… (More)
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Highly Cited
1993
Highly Cited
1993
We have characterized a new selenium-dependent glutathione peroxidase, GSHPx-GI, by expressing a GSHPx-GI cDNA isolated from… (More)
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