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glutathione peroxidase 1

Known as: Cellular Glutathione Peroxidase, GPX1 Protein, EC 1.11.1.9 
Glutathione peroxidase 1 (203 aa, ~22 kDa) is encoded by the human GPX1 gene. This protein plays a role in glutathione metabolism, peroxide reduction… Expand
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Glutathione peroxidase-1 (GPx-1) is a selenocysteine-containing enzyme that plays a major role in the reductive detoxification of… Expand
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Highly Cited
2008
Highly Cited
2008
Glutathione peroxidase (GPx) is a widespread protein superfamily found in many organisms throughout all kingdoms of life… Expand
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Highly Cited
2004
Highly Cited
2004
Insulin resistance, a hallmark of type 2 diabetes, is associated with oxidative stress. However, the role of reactive oxygen… Expand
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Highly Cited
2004
Highly Cited
2004
Along with superoxide dismutase, glutathione peroxidase 1 is one of the cellular antioxidant enzymes that have a key role in… Expand
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Highly Cited
2003
Highly Cited
2003
A role for allelic variation within the gene for the antioxidant selenoprotein glutathione peroxidase 1 (GPx-1) in the risk or… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Cellular antioxidant enzymes such as glutathione peroxidase 1 and superoxide dismutase have a central role in the… Expand
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Highly Cited
2002
Highly Cited
2002
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide and organic hydroperoxide by glutathione and functions in the… Expand
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Highly Cited
1997
Highly Cited
1997
Glutathione peroxidase, a selenium-containing enzyme, is believed to protect cells from the toxicity of hydroperoxides. The… Expand
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Highly Cited
1994
Highly Cited
1994
The sites of synthesis of extracellular (E) glutathione peroxidase (GPX), a unique selenoglycoprotein present in plasma, are not… Expand
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Highly Cited
1993
Highly Cited
1993
We have characterized a new selenium-dependent glutathione peroxidase, GSHPx-GI, by expressing a GSHPx-GI cDNA isolated from… Expand
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