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glutathione hydrolase activity

Known as: gamma-glutamyltranspeptidase activity, glutathionase activity 
Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. [EC:3.4.19.13, GOC:imk]
National Institutes of Health

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Highly Cited
2018
Highly Cited
2018
The ketogenic diet (KD) is used to treat refractory epilepsy, but the mechanisms underlying its neuroprotective effects remain… Expand
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2005
2005
To study the effects of aluminium (Al) on glutathione (GSH) metabolism in the small intestine, adult male Wistar rats were orally… Expand
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2002
2002
Differentiation of hepatic precursor cells in the biliary lineage has rarely been investigated, owing to the lack of convenient… Expand
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2000
2000
The comparative effectiveness of β-carotene (BC) and retinoic acid (RA) was investigated against two-stage rat liver… Expand
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1996
1996
The role of hepatically derived metabolites was studied in rats treated with a nephrotoxic dose of acetaminophen (APAP, 1000 mg… Expand
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Highly Cited
1991
Highly Cited
1991
The cyanomorpholino derivative of doxorubicin (MRA-CN) is a DNA intercalator and alkylator that is a highly potent cytotoxin, non… Expand
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1990
1990
The aim of this study was to set up an in vitro system to study nephrotoxicity of xenobiotics which allows exposure at low… Expand
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Highly Cited
1988
Highly Cited
1988
Acetaminophen (AA) is converted to a toxic electrophile that may subsequently form a glutathione conjugate (AA-GS). In addition… Expand
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Highly Cited
1984
Highly Cited
1984
The effect of nafenopin and phenobarbitone upon the distribution of gamma-glutamyltranspeptidase activity and epoxide hydrolase… Expand
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Highly Cited
1980
Highly Cited
1980
A cascade of events leading to hypertrophy has been proposed and implicated in growth regulation in a variety of normal and… Expand
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