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glutathione hydrolase activity

Known as: gamma-glutamyltranspeptidase activity, glutathionase activity 
Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. [EC:3.4.19.13, GOC:imk]
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
In vitro differentiation of WB-F344 rat liver epithelial cells into the biliary lineage.
Differentiation of hepatic precursor cells in the biliary lineage has rarely been investigated, owing to the lack of convenient… 
2000
2000
Further Evidence for Chemopreventive Potential of β-Carotene Against Experimental Carcinogenesis: Diethylnitrosamine-Initiated and Phenobarbital-Promoted Hepatocarcinogenesis Is Prevented More…
The comparative effectiveness of β-carotene (BC) and retinoic acid (RA) was investigated against two-stage rat liver… 
1991
1991
Estrogen receptor, epidermal growth factor receptor and cellular ploidy in elutriated subpopulations of hepatocytes during liver tumor promotion by 17 alpha-ethinylestradiol in rats.
17 alpha-Ethinylestradiol (EE2)-mediated promotion of diethylnitrosamine (DEN)-initiated liver tumors was evaluated in distinct… 
1985
1985
Effect of thiol-activated toxins (streptolysin O, alveolysin, and theta toxin) on the generation of leukotrienes and leukotriene-inducing and -metabolizing enzymes from human polymorphonuclear…
The generation of leukotrienes (LTC4, LTD4, LTE4, and LTB4; 12-epi-LTB4 isomer) from human granulocytes by thiol-activated toxins… 
1985
1985
Characterization of Dimethylnitrosamineinduced Focal and Nodular Lesions in the Livers of Newborn Mice
Newborn Swiss-Webster mice were given an intraperitoneal injection of 25 μg of dimethylnitrosamine. At weaning they began… 
Highly Cited
1984
Highly Cited
1984
Inhibitory effect of nafenopin upon the development of diethylnitrosamine-induced enzyme-altered foci within the rat liver.
The effect of nafenopin and phenobarbitone upon the distribution of gamma-glutamyltranspeptidase activity and epoxide hydrolase… 
1984
1984
Human plasma glutathione oxidation in normal and pathological conditions.
Reduced glutathione added to human plasma disappears rapidly, and it is concomitantly recovered in its oxidized form. This… 
1984
1984
Leakage of glutathione from bacterial cells caused by inhibition of gamma-glutamyltranspeptidase
Glutathione leaked from cells of Proteus mirabilis grown in medium containing an inhibitor of gamma-glutamyltranspeptidase. In… 
1982
1982
Microsomal enzyme induction in children: the influence of carbamazepine treatment on antipyrine kinetics, 6 beta-hydroxycortisol excretion and plasma gamma-glutamyltranspeptidase activity.
1 The influence of carbamazepine (CBZ) therapy on saliva antipyrine kinetics, urinary 6 beta-hydroxycortisol excretion and plasma… 
Highly Cited
1980
Highly Cited
1980
Prolonged ornithine decarboxylase induction in regenerating carcinogen-treated liver.
A cascade of events leading to hypertrophy has been proposed and implicated in growth regulation in a variety of normal and… 
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