glutathione S-transferase pi

Known as: GST Class-phi, GST Class-Pi, Glutathione S-Transferase pi [Chemical/Ingredient] 
A glutathione transferase that catalyzes the conjugation of electrophilic substrates to GLUTATHIONE. This enzyme has been shown to provide cellular… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
010020019712017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Glutathione S-transferase Pi (GSTpi) is a marker protein in many cancers and high levels are linked to drug resistance, even when… (More)
Is this relevant?
2003
2003
Glutathione S-transferase pi (GST-pi), a Phase II detoxification enzyme, has recently been implicated in protection against… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Somatic inactivation of the glutathione S-transferase-pi gene (GSTP1) via CpG island hypermethylation occurs early during… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Members of the glutathione S-transferase (GST) superfamily are important in cellular defense mechanisms. These enzymes… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
In this paper, we provide direct evidence that glutathione S-transferase pi (GSTpi) detoxifies cisplatin (CDDP). We used human… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Glutathione S-transferases (GSTs) are a family of isoenzymes that play an important role in protecting cells from cytotoxic and… (More)
  • table 1
  • figure 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Previous studies have identified allelic variants of the human glutathione transferase (GST) Pi gene and showed that the two… (More)
  • figure 1
  • table I
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Two variant glutathione S-transferase cDNAs have been described at the GSTP1 locus, which differ by a single base pair (A-G… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Hypermethylation of regulatory sequences at the locus of the pi-class glutathione S-transferase gene GSTP1 was detected in 20 of… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
1990
1990
A series of glutathione S-transferase pi (GST-pi) transfectant cell lines have been constructed in activated c-H-ras-transformed… (More)
Is this relevant?