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glutamate-cysteine ligase activity

Known as: gamma-glutamyl-L-cysteine synthetase activity, L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity, gamma-glutamylcysteine synthetase activity 
Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate. [EC:6.3.2.2, RHEA:13288]
National Institutes of Health

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Glutamate-Cysteine Ligase

Papers overview

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Review
2009
Review
2009
Antioxidant therapy in retinitis pigmentosa
Increasing evidence suggests that oxidative stress contributes to the pathogenesis of many neurodegenerative disorders, including… 
1994
1994
Perinatal development of gamma-glutamylcysteine synthetase activity in Sprague-Dawley rats
1984
1984
Glutathione-dependent yield and repair of single-strand DNA breaks in irradiated cells.
The yield and rejoining of single-strand DNA breaks (ssb) was investigated after irradiation of cells which were deficient in… 
1984
1984
Significance of glutathione S-conjugate for glutathione metabolism in human erythrocytes.
The significance of glutathione S-conjugate in the regulation of glutathione synthesis was studied using human erythrocyte gamma… 
1983
1983
A reappraisal of the gamma-glutamylcysteine synthetase activity in haemolysates from normal erythrocytes by two different methods.
gamma-Glutamylcysteine synthetase catalyses the combination of L-glutamate and L-cysteine to form gamma-glutamylcysteine with a…