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glucosylceramide metabolic process

Known as: glucosylceramide metabolism 
The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in… Expand
2008
2008
The study described in this thesis was conducted with the aim of developing lipophilic iminosugars as selective inhibitors for… Expand
Highly Cited
2007
Highly Cited
2007
In this article, we present a straightforward synthesis of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives… Expand
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Highly Cited
2007
Highly Cited
2007
The primary catabolic pathway for glucosylceramide is catalyzed by the lysosomal enzyme glucocerebrosidase that is defective in… Expand
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2005
2005
A series of 13 aminocyclitol derivatives belonging to two different families is described. Their configuration is governed by the… Expand
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Highly Cited
2000
Highly Cited
2000
We used a potent inhibitor of glucosylceramide synthase to test whether substrate deprivation could lower globotriaosylceramide… Expand
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Highly Cited
1998
Highly Cited
1998
Gaucher disease is caused by mutations in the gene encoding the lysosomal enzyme glucocerebrosidase (GC). Three clinical types of… Expand
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Highly Cited
1996
Highly Cited
1996
Multidrug-resistant (MDR) tumors and cancer cell lines demonstrate a wide variety of biochemical changes. In this study we used… Expand
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