glucose-regulated protein 170
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BiP (immunoglobulin heavy-chain binding protein) is the endoplasmic reticulum (ER) orthologue of the Hsp70 family of molecular… Expand Co-translational transport of polypeptides into the endoplasmic reticulum (ER) involves the Sec61 channel and additional… Expand Recent genetic work characterized homozygous mutations in the SIL1 gene as cause for the neurodegeneration that is associated… Expand When used as vaccines, tumor-derived stress proteins can elicit antitumor immune responses. For members of the hsp70 superfamily… Expand In alpha1-antitrypsin (alpha1-AT) deficiency, a mutant form of alpha1-AT polymerizes in the endoplasmic reticulum (ER) of liver… Expand We demonstrate the existence of a large endoplasmic reticulum (ER)-localized multiprotein complex that is comprised of the… Expand Several studies have confirmed that certain stress proteins can function as potent vaccines against a specific cancer when… Expand Both the Grp170 and Hsp110 families represent relatively conserved and distinct sets of stress proteins, within a more diverse… Expand Thyroglobulin (Tg), the major protein secreted by thyroid epithelial cells and precursor of thyroid hormones, is a large dimeric… Expand Protein transport into the mammalian endoplasmic reticulum depends on nucleoside triphosphates. Photoaffinity labelling of… Expand