glucose-6-phosphate dehydrogenase activity

Known as: NADP-glucose-6-phosphate dehydrogenase activity, G6PDH, 6-phosphoglucose dehydrogenas 
Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+. [EC:1.1.1.49]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
020406019482016

Papers overview

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2011
2011
How anti-neoplastic agents induce MDR (multidrug resistance) in cancer cells and the role of GSH (glutathione) in the activation… (More)
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2008
2008
Oocyte selection based on glucose-6-phosphate dehydrogenase (G6PDH) activity has been successfully used to differentiate between… (More)
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Highly Cited
2007
Highly Cited
2007
Hyperaldosteronism is associated with impaired vascular reactivity; however, the mechanisms by which aldosterone promotes… (More)
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2003
2003
Disruption of the ZWF1 gene encoding glucose-6-phosphate dehydrogenase (G6PDH) has been shown to reduce the xylitol yield and the… (More)
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2003
2003
Reducing equivalents in the form of NADPH are essential for many enzymatic steps involved in the biosynthesis of cellular… (More)
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Highly Cited
1999
Highly Cited
1999
The intracellular redox potential plays an important role in cell survival. The principal intracellular reductant NADPH is mainly… (More)
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Highly Cited
1999
Highly Cited
1999
The protective activity of small stress proteins (sHsp) against H2O2-mediated cell death in the highly sensitive murine L929… (More)
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Highly Cited
1998
Highly Cited
1998
The intracellular redox potential, which is determined by the level of oxidants and reductants, has been shown to play an… (More)
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Highly Cited
1986
Highly Cited
1986
The activities of the hexose monophosphate pathway enzymes glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase… (More)
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1984
1984
The hormonal and nutritional regulation of glucose 6-phosphate dehydrogenase (G6PDH; EC 1.1.1.49) was studied in primary cultures… (More)
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