glucokinase activity

Known as: ATP:D-glucose 6-phosphotransferase activity, glucokinase (phosphorylating), glucose kinase activity 
Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate. [EC:2.7.1.2]
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Genome-wide association studies have identified a number of signals for both Type 2 Diabetes and related quantitative traits. For… (More)
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Highly Cited
2008
Highly Cited
2008
We investigated the effect of curcumin on insulin resistance and glucose homeostasis in male C57BL/KsJ-db/db mice and their age… (More)
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Highly Cited
2001
Highly Cited
2001
We have previously reported that splanchnic glucose uptake, hepatic glycogen synthesis, and hepatic glucokinase activity are… (More)
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Highly Cited
2000
Highly Cited
2000
The glucokinase regulatory protein (GKRP) inhibits glucokinase competitively with respect to glucose by forming a protein-protein… (More)
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Highly Cited
2000
Highly Cited
2000
Insulin-induced stimulation of muscle glucose uptake (MGU) is impaired in people with type 2 diabetes. To determine whether… (More)
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Highly Cited
1996
Highly Cited
1996
Glucokinase reversibly partitions between a bound and a free state in the hepatocyte in response to the metabolic status of the… (More)
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Highly Cited
1995
Highly Cited
1995
Because of the demonstration of a genetic linkage between glucokinase and Type II diabetes, and the central role of glucokinase… (More)
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1990
1990
In this study, we have used isolated pancreatic islets cultured for 7 days in 3 or 30 mM glucose to explore whether glucokinase… (More)
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Highly Cited
1988
Highly Cited
1988
Streptozotocin diabetic rats showed more than a 4-fold increase in blood glucose levels, whereas hepatic glycogen, fructose 2,6… (More)
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Highly Cited
1987
Highly Cited
1987
M. Kuwajima, C. B. Newgard, D. W. Foster, and J. D. McGarry (1986, J. Biol. Chem. 261, 8849-8853) have concluded that the reason… (More)
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