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glionitrin A

 
National Institutes of Health

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Diketopiperazines

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2014
2014
Glionitrin A, a new diketopiperazine disulfide, activates ATM-ATR-Chk1/2 via 53BP1 phosphorylation in DU145 cells and shows antitumor effect in xenograft model.
In a recent study, we isolated the diketopiperazine disulfide glionitrin A from the co-culture broth of a mine drainage-derived… Expand
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2012
2012
Identification of the urinary metabolites of glionitrin A in rats using ultra-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry.
Glionitrin A (GN A) is a new diketopiperazine disulfide with an aromatic nitro group, which is isolated from the coculture of an… Expand
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2012
2012
Identification of the urinary metabolites of glionitrin A in rats using ultra-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry
 
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Highly Cited
2009
Highly Cited
2009
Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes.
The nutrient conditions present in abandoned coal mine drainages create an extreme environment where defensive and offensive… Expand
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2009
2009
Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes
 
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