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glembatumumab vedotin

An antibody-drug conjugate, consisting of the fully human monoclonal antibody CR011 directed against glycoprotein NMB (GPNMB) and conjugated via a… 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Background gpNMB is an internalizable transmembrane protein overexpressed in ˜40% of TNBC, and associated with a worse prognosis… 
2017
2017
109Background: gpNMB is an internalizable transmembrane glycoprotein expressed in melanoma and multiple other tumor types. The… 
2016
2016
Cure rates for children and young adults with osteosarcoma have remained stagnant over the past three decades. Targeting… 
2016
2016
1st Complete Response A Phase 2 Study of Glembatumumab Vedotin (GV), an Antibody-Drug Conjugate (ADC) Targeting gpNMB, in…