germinal center formation

The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2018
010203019712018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B cells and targeted by somatic mutations in B… (More)
Is this relevant?
Highly Cited
2012
Highly Cited
2012
T follicular helper (Tfh) cells promote T cell-dependent humoral immune responses by providing T cell help to B cells and by… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
CD4(+) T cells deficient in signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) exhibit a selective… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Commensal microbes can have a substantial impact on autoimmune disorders, but the underlying molecular and cellular mechanisms… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Germinal centers are critical for affinity maturation of antibody (Ab) responses. This process allows the production of high… (More)
  • figure 1
  • figure 3
  • figure 2
  • table I
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The gene encoding the BCL-6 transcriptional repressor is frequently translocated and mutated in diffuse large cell lymphoma. Mice… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Humoral immune responses were characterized in mouse strains lacking either or both B7 molecules. Mice deficient in both B7-1 and… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Previous studies have demonstrated that the T cell costimulatory molecule, CD28, is important in the development of humoral… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
An engagement of CD40 with CD40 ligand (CD40L) expressed on activated T cells is known to provide an essential costimulatory… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
gp39, the ligand for CD40 expressed on activated CD4+ T helper cells, is required for the generation of antibody responses to T… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?