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germ cell nuclear factor

Known as: Retinoid Receptor Related Testis Associated Receptor, Retinoid Receptor-Related Testis-Associated Receptor, Nuclear Receptor NR6A1 
An orphan nuclear receptor expressed mainly in the GERM CELLS of GONADS. It functions as a transcription factor that binds to a direct repeat of the… Expand
National Institutes of Health

Related topics

Related topics

11 relations
In BloodNR6A1 geneProcess of secretionagonists
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Narrower (2)

NR6A1 protein, humanNr6a1 protein, mouse

Papers overview

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Highly Cited
2007
Highly Cited
2007
Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1).
The number of vertebrae in pigs varies and is associated with meat productivity. Wild boars, which are ancestors of domestic pigs… Expand
Review
2005
Review
2005
The germ cell nuclear factor (GCNF)
  • C. Zechel
  • Molecular reproduction and development
  • 2005
    • Corpus ID: 39315293
The germ cell nuclear factor (GCNF), which is also known as RTR (retinoid receptor‐related testis‐associated receptor) is a… Expand
Highly Cited
2001
Highly Cited
2001
Mouse germline restriction of Oct4 expression by germ cell nuclear factor.
The POU-domain transcription factor Oct4 is essential for the maintenance of the mammalian germline. In this study, we show that… Expand
Highly Cited
2001
Highly Cited
2001
Loss of Orphan Receptor Germ Cell Nuclear Factor Function Results in Ectopic Development of the Tail Bud and a Novel Posterior Truncation
ABSTRACT The dynamic embryonic expression of germ cell nuclear factor (GCNF), an orphan nuclear receptor, suggests that it may… Expand
Highly Cited
1999
Highly Cited
1999
Characterization of the DNA-Binding and Dimerization Properties of the Nuclear Orphan Receptor Germ Cell Nuclear Factor
ABSTRACT The orphan receptor germ cell nuclear factor (GCNF) is a member of the superfamily of nuclear receptors. During… Expand
Highly Cited
1998
Highly Cited
1998
Germ cell nuclear factor is a response element-specific repressor of transcription.
We have shown that the orphan receptor Germ Cell Nuclear Factor (GCNF) binds to a direct repeat of the sequence AGGTCA with zero… Expand
Highly Cited
1997
Highly Cited
1997
Characterization of the Response Element and DNA Binding Properties of the Nuclear Orphan Receptor Germ Cell Nuclear Factor/Retinoid Receptor-related Testis-associated Receptor*
Recently, we have reported the cloning of the germ cell-specific, nuclear orphan receptor germ cell nuclear factor (GCNF)/RTR. In… Expand
Highly Cited
1997
Highly Cited
1997
Characterization of germ cell-specific expression of the orphan nuclear receptor, germ cell nuclear factor.
Nuclear receptors, such as those for androgens, estrogens, and progesterones, control many reproductive processes. Proteins with… Expand
1996
1996
Characterization of the human germ cell nuclear factor gene.
A cDNA clone encoding the germ cell nuclear factor, GCNF, a member of the nuclear receptor superfamily has been isolated from the… Expand
Highly Cited
1995
Highly Cited
1995
RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis.
We have identified and cloned a novel member of the nuclear receptor superfamily from murine testis, referred to as retinoid… Expand
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