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germ cell nuclear factor

Known as: Retinoid Receptor Related Testis Associated Receptor, Retinoid Receptor-Related Testis-Associated Receptor, Nuclear Receptor NR6A1 
An orphan nuclear receptor expressed mainly in the GERM CELLS of GONADS. It functions as a transcription factor that binds to a direct repeat of the… Expand
National Institutes of Health

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11 relations
In BloodNR6A1 geneProcess of secretionagonists
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Narrower (2)

NR6A1 protein, humanNr6a1 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Suppression of Oct4 by Germ Cell Nuclear Factor Restricts Pluripotency and Promotes Neural Stem Cell Development in the Early Neural Lineage
The earliest murine neural stem cells are leukemia inhibitory factor (LIF)-dependent, primitive neural stem cells, which can be… Expand
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Highly Cited
2007
Highly Cited
2007
Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1).
The number of vertebrae in pigs varies and is associated with meat productivity. Wild boars, which are ancestors of domestic pigs… Expand
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Highly Cited
2004
Highly Cited
2004
Differential Oocyte-Specific Expression of Cre Recombinase Activity in GDF-9-iCre, Zp3cre, and Msx2Cre Transgenic Mice1
Abstract Oocyte-specific deletion of ovarian genes using Cre/loxP technology provides an excellent tool to understand their… Expand
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2003
2003
Expression of the Orphan Nuclear Receptor, Germ Cell Nuclear Factor, in Mouse Gonads and Preimplantation Embryos1
Abstract Germ cell nuclear factor (GCNF, NR6A1) is an orphan member of the nuclear receptor superfamily and functions as a… Expand
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Highly Cited
2001
Highly Cited
2001
Mouse germline restriction of Oct4 expression by germ cell nuclear factor.
The POU-domain transcription factor Oct4 is essential for the maintenance of the mammalian germline. In this study, we show that… Expand
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Highly Cited
2001
Highly Cited
2001
Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation.
The dynamic embryonic expression of germ cell nuclear factor (GCNF), an orphan nuclear receptor, suggests that it may play an… Expand
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1999
1999
Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor.
The orphan receptor germ cell nuclear factor (GCNF) is a member of the superfamily of nuclear receptors. During development, GCNF… Expand
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1998
1998
Germ cell nuclear factor is a response element-specific repressor of transcription.
We have shown that the orphan receptor Germ Cell Nuclear Factor (GCNF) binds to a direct repeat of the sequence AGGTCA with zero… Expand
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1997
1997
Characterization of the Response Element and DNA Binding Properties of the Nuclear Orphan Receptor Germ Cell Nuclear Factor/Retinoid Receptor-related Testis-associated Receptor*
Recently, we have reported the cloning of the germ cell-specific, nuclear orphan receptor germ cell nuclear factor (GCNF)/RTR. In… Expand
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1996
1996
Characterization of the human germ cell nuclear factor gene.
A cDNA clone encoding the germ cell nuclear factor, GCNF, a member of the nuclear receptor superfamily has been isolated from the… Expand
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