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germ cell nuclear factor
Known as:
Retinoid Receptor Related Testis Associated Receptor
, Retinoid Receptor-Related Testis-Associated Receptor
, Nuclear Receptor NR6A1
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An orphan nuclear receptor expressed mainly in the GERM CELLS of GONADS. It functions as a transcription factor that binds to a direct repeat of the…
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National Institutes of Health
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Related topics
Related topics
11 relations
In Blood
NR6A1 gene
Process of secretion
agonists
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Narrower (2)
NR6A1 protein, human
Nr6a1 protein, mouse
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1).
S. Mikawa
,
T. Morozumi
,
+5 authors
T. Awata
Genome Research
2007
Corpus ID: 41630473
The number of vertebrae in pigs varies and is associated with meat productivity. Wild boars, which are ancestors of domestic pigs…
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Review
2005
Review
2005
The germ cell nuclear factor (GCNF)
C. Zechel
Molecular Reproduction and Development
2005
Corpus ID: 39315293
The germ cell nuclear factor (GCNF), which is also known as RTR (retinoid receptor‐related testis‐associated receptor) is a…
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Highly Cited
2003
Highly Cited
2003
Expression of the Orphan Nuclear Receptor, Germ Cell Nuclear Factor, in Mouse Gonads and Preimplantation Embryos1
Zi-Jian Lan
,
Peili Gu
,
Xueping Xu
,
A. Cooney
Biology of Reproduction
2003
Corpus ID: 10782302
Abstract Germ cell nuclear factor (GCNF, NR6A1) is an orphan member of the nuclear receptor superfamily and functions as a…
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Highly Cited
2001
Highly Cited
2001
Loss of Orphan Receptor Germ Cell Nuclear Factor Function Results in Ectopic Development of the Tail Bud and a Novel Posterior Truncation
A. Chung
,
D. Katz
,
+4 authors
B. O'Malley
Molecular and Cellular Biology
2001
Corpus ID: 1718973
ABSTRACT The dynamic embryonic expression of germ cell nuclear factor (GCNF), an orphan nuclear receptor, suggests that it may…
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Highly Cited
2001
Highly Cited
2001
Mouse germline restriction of Oct4 expression by germ cell nuclear factor.
G. Fuhrmann
,
A. Chung
,
+6 authors
A. Cooney
Developmental Cell
2001
Corpus ID: 497339
Highly Cited
1999
Highly Cited
1999
Characterization of the DNA-Binding and Dimerization Properties of the Nuclear Orphan Receptor Germ Cell Nuclear Factor
H. Greschik
,
J. Wurtz
,
P. Hublitz
,
Fabian Köhler
,
D. Moras
,
R. Schüle
Molecular and Cellular Biology
1999
Corpus ID: 44545494
ABSTRACT The orphan receptor germ cell nuclear factor (GCNF) is a member of the superfamily of nuclear receptors. During…
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Highly Cited
1998
Highly Cited
1998
Germ cell nuclear factor is a response element-specific repressor of transcription.
A. Cooney
,
G. Hummelke
,
T. Herman
,
F. Chen
,
K. Jackson
Biochemical and Biophysical Research…
1998
Corpus ID: 32852596
We have shown that the orphan receptor Germ Cell Nuclear Factor (GCNF) binds to a direct repeat of the sequence AGGTCA with zero…
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Highly Cited
1997
Highly Cited
1997
Characterization of the Response Element and DNA Binding Properties of the Nuclear Orphan Receptor Germ Cell Nuclear Factor/Retinoid Receptor-related Testis-associated Receptor*
Zhong Hua Yan
,
A. Medvedev
,
T. Hirose
,
H. Gotoh
,
A. Jetten
Journal of Biological Chemistry
1997
Corpus ID: 23603194
Recently, we have reported the cloning of the germ cell-specific, nuclear orphan receptor germ cell nuclear factor (GCNF)/RTR. In…
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Highly Cited
1997
Highly Cited
1997
Characterization of germ cell-specific expression of the orphan nuclear receptor, germ cell nuclear factor.
D. Katz
,
C. Niederberger
,
G. Slaughter
,
A. Cooney
Endocrinology
1997
Corpus ID: 26111138
Nuclear receptors, such as those for androgens, estrogens, and progesterones, control many reproductive processes. Proteins with…
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Highly Cited
1995
Highly Cited
1995
RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis.
T. Hirose
,
D. A. O’Brien
,
A. Jetten
Gene
1995
Corpus ID: 45970409
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