geranylgeranylglycerol-phosphate geranylgeranyltransferase activity

Known as: geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity, geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity 
Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
01219972017

Papers overview

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2017
2017
OBJECTIVE RNA interference was used to silence geranylgeranyltransferase Ⅰ(GGTase-Ⅰ) in vitro and to study the effect of GGTase… (More)
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2003
2003
Agrin activates the transmembrane tyrosine kinase MuSK to mediate acetylcholine receptor (AChR) clustering at the neuromuscular… (More)
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2003
2003
Platelet-derived growth factor (PDGF) is a potent inducer of vascular smooth muscle cell (VSMC) migration, whereas insulin, in… (More)
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Review
2000
Review
2000
The fact that proteins such as Ras, Rac and RhoA require farnesylation or geranylgeranylation to induce malignant transformation… (More)
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1997
1997
Inhibition of farnesyltransferase (FTase) has been thoroughly investigated as a strategy to discover novel anticancer drugs… (More)
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