geranylgeranyl pyrophosphate

Known as: GGPP diphosphate, diphosphoric acid, mono(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl) ester, (E,E,E)-, GGPP cpd 
 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
A common strategy of metabolic engineering is to increase the endogenous supply of precursor metabolites to improve pathway… (More)
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Highly Cited
2008
Highly Cited
2008
In many organisms, various enzymes mediate site-specific carotenoid cleavage to generate biologically active apocarotenoids… (More)
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2008
2008
Cleavage of the amyloid precursor protein (APP) by beta- and gamma-secretases results in generation of the amyloid-beta protein… (More)
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2007
2007
A primary cellular target of the clinical nitrogenous bisphosphonates is the isoprenoid biosynthetic pathway. Specifically these… (More)
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2006
2006
Modification of GTPases with isoprenoid molecules derived from geranylgeranyl pyrophosphate or farnesyl pyrophosphate is an… (More)
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Highly Cited
2005
Highly Cited
2005
Hepatitis C virus (HCV) infection is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Our… (More)
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Highly Cited
2004
Highly Cited
2004
The tomato (Lycopersicon esculentum) mutant def-1, which is deficient in induced jasmonic acid (JA) accumulation upon wounding or… (More)
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Highly Cited
2004
Highly Cited
2004
Rice (Oryza sativa) produces momilactone diterpenoids as both phytoalexins and allelochemicals. Accordingly, the committed step… (More)
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2001
2001
ATP-binding cassette transporter A1 (ABCA1) mediates an active efflux of cholesterol and phospholipids and is mutated in patients… (More)
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Highly Cited
2000
Highly Cited
2000
Geranylgeranyl diphosphate (GGPP) is the precursor for the biosynthesis of gibberellins, carotenoids, chlorophylls, isoprenoid… (More)
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