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gepirone

Known as: 4,4-dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-2,6-piperidinedione 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (4)

Anti-Anxiety AgentsAntidepressive AgentsPyrimidinesSerotonin Agonists

Narrower (3)

BMY 13805MJ 13805Org 13011
Gepirone Hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1998
Review
1998
Pharmacologic Treatments Effective in Both Generalized Anxiety Disorder and Major Depressive Disorder: Clinical and Theoretical Implications
Objective: To review the efficacy of anxiolytics (alprazolam and azapirones) in major depressive disorder (MDD) and that of… 
Highly Cited
1997
Highly Cited
1997
Modulation of the Discriminative Stimulus Properties of Cocaine: Comparison of the Effects of Fluoxetine with 5-HT1A and 5-HT1B Receptor Agonists
Highly Cited
1995
Highly Cited
1995
Characterization of 5-hydroxytryptamine1A properties of flesinoxan: In Vivo electrophysiology and hypothermia study
Highly Cited
1990
Highly Cited
1990
Antidepressant-like action of 8-OH-DPAT, a 5-HT1A agonist, in the learned helplessness paradigm: evidence for a postsynaptic mechanism
Highly Cited
1990
Highly Cited
1990
8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats
Highly Cited
1990
Highly Cited
1990
Behavioural effects of serotonin agonists and antagonists in the rat and marmoset
Highly Cited
1988
Highly Cited
1988
Activation of the 5-HT1A receptor subtype increases rat plasma ACTH concentration.
Highly Cited
1988
Highly Cited
1988
Alterations of central serotonin and dopamine turnover in rats treated with ipsapirone and other 5-hydroxytryptamine1A agonists with potential anxiolytic properties.
Measurements of tissue levels of monoamines and their metabolites, and of the rates of 5-hydroxytryptophan and dihydroxy… 
Highly Cited
1987
Highly Cited
1987
Gepirone in Anxiety: A Pilot Study
Ten patients suffering from generalized anxiety disorder were treated, after a single-blind placebo washout week, with the… 
Highly Cited
1987
Highly Cited
1987
Behavioral effects of several new anxiolytics and putative anxiolytics.
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