gepirone

Known as: 4,4-dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-2,6-piperidinedione 
 
National Institutes of Health

Papers overview

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Review
2003
Review
2003
The role of serotonin (5-hydroxytryptamine; 5-HT) in the treatment of depressive and anxiety disorders is underscored by the… (More)
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2000
2000
The potential role of 5-hydroxytryptamine (5-HT) in anxiety has been the subject of much research, most of it addressed to the… (More)
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Highly Cited
1995
Highly Cited
1995
This study demonstrated that distinct patterns of active behaviors are produced by antidepressants that selectively inhibit… (More)
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1994
1994
It has proven difficult to demonstrate and study the “anxiogenic” quality of drug withdrawal states in animals. Ultrasonic… (More)
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1990
1990
The effects of the selective 5-HT1A receptor agonist gepirone (10 and 20 mg orally) on neuroendocrine function and temperature… (More)
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1988
1988
The effects of the nonbenzodiazepine anxiolytic agents, buspirone, gepirone and ipsapirone on body temperature and corticosterone… (More)
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1988
1988
Fear potentiation of the acoustic startle reflex was produced by eliciting startle responses in the presence of a light that had… (More)
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Highly Cited
1987
Highly Cited
1987
The sustained administration of the 5-HT1A agonist gepirone (15 mg/kg/day, s.c.) in the rat produced an initial decrease of the… (More)
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1987
1987
Ten patients suffering from generalized anxiety disorder were treated, after a single-blind placebo washout week, with the… (More)
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1986
1986
The literature describing the role of serotonin (5-HT) in the mediation of anxiety is a controversial one. Serotonergic… (More)
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