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general transcription factor IIIC1 alpha subunit

Known as: transcription factor TFIIIC1, TFIIIC220, TFIIIC1 
General transcription factor 3C polypeptide 1 (2109 aa, ~239 kDa) is encoded by the human GTF3C1 gene. This protein is required for RNA polymerase… 
National Institutes of Health

Related topics

Related topics

10 relations
Basal transcription factor genesDNA-Binding ProteinsGTF3C1 geneGTF3C1 wt Allele

Broader (1)

transcription factor TFIIIC

Papers overview

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1999
1999
The RNA polymerase III-recruiting factor TFIIIB induces a DNA bend between the TATA box and the transcriptional start site.
TFIIIB, the RNA polymerase III-recruiting factor of Saccharomyces cerevisiae, may be assembled upstream of the transcriptional… 
Highly Cited
1997
Highly Cited
1997
Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition.
Transcription by RNA polymerase III (Pol III) requires multiple general initiation factors that, in isolated form, assemble onto… 
Highly Cited
1997
Highly Cited
1997
Functional dissection of the B" component of RNA polymerase III transcription factor IIIB: a scaffolding protein with multiple roles in assembly and initiation of transcription
Transcription factor IIIB (TFIIIB), the central transcription factor of Saccharomyces cerevisiae RNA polymerase III, is composed… 
Highly Cited
1994
Highly Cited
1994
Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC
Transcription factor IIIC (TFIIIC) is required for the assembly of a preinitiation complex on 5S RNA, tRNA, and adenovirus VA RNA… 
Highly Cited
1991
Highly Cited
1991
Two essential components of the Saccharomyces cerevisiae transcription factor TFIIIB: transcription and DNA-binding properties.
RNA polymerase III transcription factor TFIIIB from Saccharomyces cerevisiae contains at least two polypeptides, with apparent… 
Highly Cited
1990
Highly Cited
1990
A transcriptionally active form of TFIIIC is modified in poliovirus-infected HeLa cells
In HeLa cells, RNA polymerase III (pol III)-mediated transcription is severely inhibited by poliovirus infection. This inhibition… 
Highly Cited
1987
Highly Cited
1987
Resolution of human transcription factor TFIIIC into two functional components.
tRNA genes and adenovirus viral-associated (VA) genes are transcribed by RNA polymerase III. Transcription of these genes in… 
1987
1987
Transcription complexes for various class III genes differ in parameters of formation and stability towards salt.
Highly Cited
1987
Highly Cited
1987
Inhibition of host cell RNA polymerase III-mediated transcription by poliovirus: inactivation of specific transcription factors
The inhibition of transcription by RNA polymerase III in poliovirus-infected cells was studied. Experiments utilizing two… 
1987
1987
Separation of TFIIIC into two functional components by sequence specific DNA affinity chromatography.
Recently, it has been shown that mammalian transcription factor IIIC (TFIIIC) activity can be separated by anion exchange FPLC… 
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