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general transcription factor IIIC1 alpha subunit

Known as: transcription factor TFIIIC1, TFIIIC220, TFIIIC1 
General transcription factor 3C polypeptide 1 (2109 aa, ~239 kDa) is encoded by the human GTF3C1 gene. This protein is required for RNA polymerase… Expand
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
BackgroundChromosome conformation capture studies suggest that eukaryotic genomes are organized into structures called… Expand
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Highly Cited
2010
Highly Cited
2010
Genome-wide occupancy profiles of five components of the RNA polymerase III (Pol III) machinery in human cells identified the… Expand
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Highly Cited
2010
Highly Cited
2010
Synthesis of tRNA and 5S rRNA by RNA polymerase (pol) III is regulated by the mTOR pathway in mammalian cells. The mTOR kinase… Expand
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Highly Cited
2008
Highly Cited
2008
Eukaryotic chromosomes reach their stable rod-shaped appearance in mitosis in a reaction dependent on the evolutionarily… Expand
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Highly Cited
2006
Highly Cited
2006
Eukaryotic genome complexity necessitates boundary and insulator elements to partition genomic content into distinct domains. We… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT We used chromatin immunoprecipitation, followed by microarray hybridization, to determine the genome-wide distribution… Expand
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Review
2000
Review
2000
SUMMARY The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to have major effects on levels of… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT Human TFIIIC is a multisubunit factor that is essential for transcription by RNA polymerase III on tRNA and virus… Expand
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Highly Cited
1999
Highly Cited
1999
The structure of the yeast RNA polymerase (pol) III was investigated by exhaustive two-hybrid screening using a library of random… Expand
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Highly Cited
1995
Highly Cited
1995
The yeast retroviruslike element Ty3 inserts at the transcription initiation sites of genes transcribed by RNA polymerase III… Expand
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