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gardiquimod

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
012320072017

Related topics

Related topics

2 relations

Broader (2)

AminoquinolinesImidazoles

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
gardiquimod
Imidazoles
Aminoquinolines

Papers overview

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2013
2013
Gardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells.
Immune response modifiers are being studied as therapeutic agents for viral infections and cancer. These molecules include… (More)
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2012
2012
Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes.
While current subunit vaccines successfully induce humoral immune responses, a need exists for vaccine strategies to elicit… (More)
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2011
2011
NTPDase1 controls IL-8 production by human neutrophils.
The ectonucleotidase NTPDase1 (CD39) terminates P2 receptor activation by the hydrolysis of extracellular nucleotides (i.e., the… (More)
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2010
2010
The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice
Toll-like receptors (TLRs) are a family of highly conserved germline-encoded pattern-recognition receptors that are essential for… (More)
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Highly Cited
2010
Highly Cited
2010
Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells.
Plasmacytoid dendritic cells (pDCs) play essential roles in directing immune responses. These cells may be particularly important… (More)
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2010
2010
Signaling through TLR7 enhances the immunosuppressive activity of murine CD4+CD25+ T regulatory cells.
Although signaling through certain TLRs is known to modulate the function of T lymphocytes, the effect of TLR7 stimulation on CD4… (More)
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2010
2010
TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity.
We previously reported that synthetic or natural Toll-like receptor (TLR) 7/8 agonists present within dead cells enhanced cell… (More)
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2010
2010
An intranasally delivered Toll-like receptor 7 agonist elicits robust systemic and mucosal responses to Norwalk virus-like particles.
Norwalk virus (NV) is an enteric pathogen from the genus Norovirus and a major cause of nonbacterial gastroenteritis in humans… (More)
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2010
2010
Assessing the immunopotency of Toll-like receptor agonists in an in vitro tissue-engineered immunological model.
SUMMARY The in vitro Peripheral Tissue Equivalent (PTE) module is a three-dimensional tissue-engineered endothelial cell/collagen… (More)
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2009
2009
Intradermal immunization improves protective efficacy of a novel TB vaccine candidate.
We have developed the Mycobacterium tuberculosis (Mtb) fusion protein (ID83), which contains the three Mtb proteins Rv1813… (More)
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