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ganglioside binding

Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more… Expand
National Institutes of Health

Papers overview

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2019
2019
Abstract. To increase the efficacy of the small amounts of therapeutic protein generally synthesized in transformed plants, we… Expand
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2014
2014
Gangliosides are major cell-surface determinants on all vertebrate neurons. Human congenital disorders of ganglioside… Expand
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2011
2011
The seven botulinum neurotoxins (BoNT) cause muscle paralysis by selectively cleaving core components of the vesicular fusion… Expand
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2011
2011
Botulinum Neurotoxins (BoNTs) are organized into seven serotypes, A-G. Although several BoNT serotypes enter neurons through… Expand
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2008
2008
Tetanus toxin (TeNT) elicits spastic paralysis through the cleavage of vesicle-associated membrane protein-2 (VAMP-2) in neurons… Expand
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2006
2006
In this study, the immunogenicities of the nontoxic H(C) fragment of tetanus toxin and derivatives lacking ganglioside binding… Expand
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2005
2005
Nontypeable Haemophilus influenzae (NTHI) are a major cause of human infections. We previously demonstrated high affinity and… Expand
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Highly Cited
2004
Highly Cited
2004
Tetanus and botulinum neurotoxins selectively invade neurons following binding to complex gangliosides. Recent biochemical… Expand
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2000
2000
Tetanus toxin binds neuronal tissue prior to internalization and trafficking to the central nervous system. Binding of the… Expand
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1999
1999
The non-toxin 50 kD C-terminus peptide of the heavy chain of tetanus H(c) contains the ganglioside binding domain of tetanus… Expand
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