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ganglioside binding

Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more… Expand
National Institutes of Health

Papers overview

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2014
2014
Gangliosides are major cell-surface determinants on all vertebrate neurons. Human congenital disorders of ganglioside… Expand
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Highly Cited
2011
Highly Cited
2011
The seven botulinum neurotoxins (BoNT) cause muscle paralysis by selectively cleaving core components of the vesicular fusion… Expand
2011
2011
Botulinum Neurotoxins (BoNTs) are organized into seven serotypes, A-G. Although several BoNT serotypes enter neurons through… Expand
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Highly Cited
2008
Highly Cited
2008
Tetanus toxin (TeNT) elicits spastic paralysis through the cleavage of vesicle-associated membrane protein-2 (VAMP-2) in neurons… Expand
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2006
2006
ABSTRACT In this study, the immunogenicities of the nontoxic HC fragment of tetanus toxin and derivatives lacking ganglioside… Expand
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2005
2005
Nontypeable Haemophilus influenzae (NTHI) are a major cause of human infections. We previously demonstrated high affinity and… Expand
Highly Cited
2004
Highly Cited
2004
Tetanus and botulinum neurotoxins selectively invade neurons following binding to complex gangliosides. Recent biochemical… Expand
Highly Cited
2000
Highly Cited
2000
Tetanus toxin binds neuronal tissue prior to internalization and trafficking to the central nervous system. Binding of the… Expand
1999
1999
The non-toxin 50 kD C-terminus peptide of the heavy chain of tetanus H(c) contains the ganglioside binding domain of tetanus… Expand
1996
1996
Ganglioside stimulated neurite outgrowth may be due to ganglioside binding to membrane proteins or to intercalation into the… Expand
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