ganglion formation

Loss-of-function mutations in PYCR2 cause hypomyelinating leukodystrophy 10 (HLD10) (MIM: 616420) characterized by postnatal… Expand

The majority of cranial sensory neurons originate in placodes in the surface ectoderm, migrating to form ganglia that connect to… Expand

BackgroundPax2;5;8 transcription factors play diverse roles in vertebrate and invertebrate organogenesis, including the… Expand

Induction of the sympathetic nervous system (SNS) from its neural crest (NC) precursors is dependent on BMP signaling from the… Expand

The boundary of gene expression of transcription factors often plays a role in making a signaling center in development. In the… Expand

The enteric nervous system (ENS) is derived from neural crest cells that migrate along the gastrointestinal tract to form a… Expand

Hirschsprung disease and Waardenburg syndrome are human genetic diseases characterized by distinct neural crest defects. Patients… Expand

Holoprosencephaly malformations, of which the fetal alcohol syndrome appears to be a mild form, can result from medial anterior… Expand

In order to give rise to the enteric nervous system (ENS), cells migrating from the neural crest must find the bowel and cease… Expand

The peripheral nervous system derives mainly from the neural crest both in the head and trunk. Using markers such as fibronectin… Expand