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gamma-butyrobetaine,2-oxoglutarate dioxygenase

Known as: gamma-Butyrobetaine Dioxygenase, Trimethylaminobutyrate Hydroxylase, gamma Butyrobetaine, 2 Oxoglutarate Dioxygenase 
An enzyme that catalyzes the HYDROXYLATION of gamma-butyrobetaine to L-CARNITINE. It is the last enzyme in the biosynthetic pathway of L-CARNITINE… 
National Institutes of Health

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7 relations
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Ability of bacterial biphenyl dioxygenases from Burkholderia sp. LB400 and Comamonas testosteroni B-356 to catalyse oxygenation of ortho-hydroxychlorobiphenyls formed from PCBs by plants.
2000
2000
Effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor, on tissue carnitine and lipid levels in rats.
MET-88, 3-(2,2,2-trimethylhydrazinium) propionate, suppresses carnitine synthesis by inhibiting (gamma-butyrobetaine hydroxylase… 
2000
2000
Carnitine transport into muscular cells. Inhibition of transport and cell growth by mildronate.
Highly Cited
1998
Highly Cited
1998
Response of Bacillus subtilis to high osmolarity: uptake of carnitine, crotonobetaine and γ-butyrobetaine via the ABC transport system OpuC.
It was found that low concentrations of the naturally occurring and structurally related betaines L-carnitine, crotonobetaine and… 
1996
1996
Inhibition of carnitine biosynthesis by valproic acid in rats--the biochemical mechanism of inhibition.
Highly Cited
1989
Highly Cited
1989
Utilization of dietary precursors for carnitine synthesis in human adults.
Endogenous synthetic pathways are presumed to be sufficient to provide adequate amounts of carnitine to meet the needs of the… 
1988
1988
Induction of indoleamine dioxygenase by interferon in mice: a study with different recombinant interferons and various cytokines.
Highly Cited
1984
Highly Cited
1984
Carnitine biosynthesis from gamma-butyrobetaine and from exogenous protein-bound 6-N-trimethyl-L-lysine by the perfused guinea pig liver. Effect of ascorbate deficiency on the in situ activity of…
The production of carnitine from peptide-bound 6-N-trimethyl-L-lysine (Lys(Me3)) or 4-N-trimethyl-aminobutyrate(gamma… 
1984
1984
Effect of vitamin C deficiency on hydroxylation of trimethylaminobutyrate to carnitine in the guinea pig.
1970
1970
Gamma-butyrobetaine hydroxylase from Pseudomonas sp AK 1.
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