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gamma-Glutamyl Hydrolase
Known as:
Folacin Conjugase
, Carboxypeptidase G
, Folate Conjugase
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Catalyzes the hydrolysis of pteroylpolyglutamic acids in gamma linkage to pterolylmonoglutamic acid and free glutamic acid. EC 3.4.19.9.
National Institutes of Health
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Related topics
Related topics
11 relations
Narrower (3)
Carboxypeptidase G1
Gamma-Glutamyl Hydrolase, human
glucarpidase
GGH gene
In Blood
Process of secretion
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
R. Mauritz
,
M. W. Bekkenk
,
+6 authors
Gerrit Jansen
Clinical Cancer Research
1998
Corpus ID: 30917718
Leukemic cells of 27 children [14 patients with initial acute lymphoblastic leukemia (iALL), 8 patients with relapsed ALL (rALL…
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1992
1992
Metabolic turnover of methotrexate polyglutamates in lysosomes derived from S180 cells. Definition of a two-step process limited by mediated lysosomal permeation of polyglutamates and activating…
J. Barrueco
,
D. F. O'Leary
,
F. Sirotnak
Journal of Biological Chemistry
1992
Corpus ID: 22374075
Highly Cited
1991
Highly Cited
1991
Pteroylpolyglutamates in human milk.
D. O’Connor
,
T. Tamura
,
M. Picciano
American Journal of Clinical Nutrition
1991
Corpus ID: 42911865
Considerable variation exists in reported values for total folate content and the pteroylpolyglutamate (PteGlun) content of human…
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Highly Cited
1990
Highly Cited
1990
Application of a tri-enzyme extraction for total folate determination in foods.
James I Martin
,
W. Landen
,
A.-G. M. Soliman
,
Ronald R. Eitenmiller
Journal - Association of Official Analytical…
1990
Corpus ID: 32097880
A tri-enzyme digestion procedure using chicken pancreas conjugase, alpha-amylase, and Pronase was evaluated to determine its…
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1986
1986
Forms of Human Milk Folacin and Variation Patterns
Cecelia M. Brown
,
Anne M. Smith
,
M F Picciano
Journal of Pediatric Gastroenterology and…
1986
Corpus ID: 39721456
Summary: The pattern of folacin in 180 human milk samples collected from 16 women was studied before and after pteroylglutamic…
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1982
1982
The folate in human milk.
J. Cooperman
,
H. Dweck
,
L. Newman
,
C. Garbarino
,
R. Lopez
American Journal of Clinical Nutrition
1982
Corpus ID: 4441441
In previous studies of the folate content of human milk, samples were prepared for assay by a method that resulted in a turbid…
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1969
1969
Malabsorption of Folate Polyglutamates in Tropical Sprue
A. Hoffbrand
,
T. Necheles
,
N. Maldonado
,
E. Horta
,
R. Santini
British medical journal
1969
Corpus ID: 22777900
Malabsorption of folate polyglutamates prepared from yeast has been shown in eight patients with untreated tropical sprue and in…
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1967
1967
Intestinal folate conjugase activity in tropical sprue.
F. Klipstein
American Journal of Clinical Nutrition
1967
Corpus ID: 4443698
1948
1948
On the specificity of chicken pancreas conjugase (gamma-glutamic acid carboxypeptidase).
A. Kazenko
,
M. Laskowski
Journal of Biological Chemistry
1948
Corpus ID: 42405624
The early studies on conjugase from chicken pancreas (1, 2) did not lead to the identification of this enzyme. Subsequent…
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Highly Cited
1946
Highly Cited
1946
Observations on vitamin Bc conjugase from hog kidney.
Bird Od
,
M. Robbins
Journal of Biological Chemistry
1946
Corpus ID: 12438852
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