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gamabufotalin

National Institutes of Health

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Bufanolides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
nnnnnnnnSequentially-targeted biomimetic nano drug system for triple-negative breast cancer ablation and lung metastasis inhibition.
Highly Cited
2019
Highly Cited
2019
RBC membrane camouflaged prussian blue nanoparticles for gamabutolin loading and combined chemo/photothermal therapy of breast cancer.
2016
2016
Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells
Deciding appropriate therapy for multiple myeloma (MM) is challenging because of the occurrence of multiple chromosomal changes… 
2016
2016
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer
Gamabufotalin (CS-6) is a major bufadienolide of Chansu, which shows desirable metabolic stability and less adverse effect in… 
2016
2016
Effects of active bufadienolide compounds on human cancer cells and CD4+CD25+Foxp3+ regulatory T cells in mitogen-activated human peripheral blood mononuclear cells.
The growth inhibitory effects of bufadienolide compounds were investigated in two intractable cancer cells, a human glioblastoma… 
2015
2015
Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin Pill following oral administration to mice.
2015
2015
Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway
Gamabufotalin (CS-6), a main active compound isolated from Chinese medicine Chansu, has been shown to strongly inhibit cancer… 
Highly Cited
2014
Highly Cited
2014
Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells
BackgroundGamabufotalin (CS-6), a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic… 
Review
2012
Review
2012
Anti-tumor activity and apoptosis-regulation mechanisms of bufalin in various cancers: new hope for cancer patients.
  • P. YinXuan Liu Qi Li
  • Asian Pacific Journal of Cancer Prevention
  • 2012
  • Corpus ID: 12830211
The induction of apoptosis in target cells is a key mechanism for most anti-tumor therapies. Bufalin is a cardiotonic steroid… 
1964
1964
A CHROMATOGRAPHIC STUDY OF THE BUFADIENOLIDES ISOLATED FROM THE VENOM OF THE PAROTID GLANDS OF BUFO PARACNEMIS LUTZ 1925.
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