galloflavin

Glycolysis is the main route for energy production in tumors. LDH-A is a key enzyme of this process and its inhibition represents… (More)

Activation of hepatic stellate cells (HSCs) is characterized by expression of extracellular matrix and loss of adipogenic… (More)

High rates of aerobic glycolysis represent a key mechanism by which endometrial cancer cells consume glucose as its primary… (More)

Altered metabolism is a critical part of cancer cell properties, but real-time monitoring of metabolomic profiles has been… (More)

High-altitude residents have lower mortality rates for ischaemic heart disease and this is ascribed to cardiac gene remodelling… (More)

Two flavonoids, jaceosidin 7-O-β-d-glucopyranosyl-(1→2)-β-d-glucopyranoside (1) and hispidulin 7-O-β-d-glucopyranosyl-(1→2)-β-d… (More)

Lactate dehydrogenase A (LDH-A) binds single stranded DNA (ssDNA) and stimulates cell transcription. Binding is prevented by NADH… (More)

Activation of the myc oncogene in cancer cells upregulates lactate dehydrogenase A (LDH-A) expression, leading to a sustained… (More)

One of the most prominent alterations in cancer cells is their strict dependence on the glycolytic pathway for ATP generation… (More)

Galloflavin (GF), a recently identified lactate dehydrogenase inhibitor, hinders the proliferation of cancer cells by blocking… (More)