furafylline

Known as: 1,8-dimethyl-3-(2'-furfuryl)-1H-purine-2,6-dione 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
0102019862018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
We evaluated the effects of 25 purified components of commonly used herbal products on the catalytic activity of cDNA-expressed… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
AIMS Chemical inhibitors of cytochrome P450 (CYP) are a useful tool in defining the role of individual CYPs involved in drug… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Cytochrome P450 chemical inhibitors are widely used to define the role of individual cytochrome P450 isozyme(s) in a metabolism… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Identifying selective inhibitors of cytochrome P450 isoforms is a useful tool in defining the role of individual cytochrome P450s… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The O-dealkylations of ethoxyresorufin and pentoxyresorufin are widely used activity probes for measuring the cytochrome P450… (More)
Is this relevant?
1994
1994
1. Furafylline inhibition of 1A2-related activity in human liver microsomal systems was characterized. This inhibition was time… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The contribution of CYP1A2 to the metabolism of the dietary heterocyclic amines, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine… (More)
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Biotransformation reactions catalyzed by human cytochrome P450 1A2 (P450 1A2) appear to play a significant role in both the… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
1. Furafylline (1,8-dimethyl-3-(2'-furfuryl)methylxanthine) is a methylxanthine derivative that was introduced as a long-acting… (More)
Is this relevant?
1987
1987
The pharmacokinetics and tolerance of repeated oral doses of furafylline were investigated in normal volunteers. In accord with… (More)
Is this relevant?