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frizzled related protein-1

Known as: Secreted Apoptosis-Related Protein 2, secreted frizzled related protein-1, Secreted Frizzled-Related Protein 1 
Secreted frizzled-related protein 1 (314 aa, ~35 kDa) is encoded by the human SFRP1 gene. This protein is involved in the modulation of Wnt signaling… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Compelling evidence have demonstrated that bulk tumors can arise from a unique subset of cells commonly termed “cancer stem cells… Expand
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Highly Cited
2009
Highly Cited
2009
Canonical Wnt signaling has been demonstrated to increase bone formation, and Wnt pathway components are being pursued as… Expand
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Highly Cited
2009
Highly Cited
2009
We evaluated the healing potential of human fetal aorta-derived CD133(+) progenitor cells and their conditioned medium (CD133… Expand
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2008
2008
Consistent with findings of Wnt pathway members involved in vascular cells, a role for Wnt/Frizzled signaling has recently… Expand
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2007
2007
Secreted frizzled-related proteins (sFRPs) are glycoproteins that are recognized as Wnt antagonists. To identify the functional… Expand
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Highly Cited
2005
Highly Cited
2005
Mechanisms controlling human bone formation remain to be fully elucidated. We have used differential display-polymerase chain… Expand
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Highly Cited
2004
Highly Cited
2004
Previous studies have associated activation of canonical Wnt signaling in osteoblasts with elevated bone formation. Here we… Expand
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Highly Cited
2004
Highly Cited
2004
UNLABELLED We determined that sFRP-1 mRNA was differentially expressed by osteoblast/stromal cell lines and that sFRP-1… Expand
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Highly Cited
2001
Highly Cited
2001
Wnt-4 signaling plays a critical role in kidney development and is associated with the epithelial conversion of the metanephric… Expand
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Highly Cited
2000
Highly Cited
2000
Secreted Frizzled-related protein-1 (sFRP-1) contains a cysteine-rich domain homologous to the putative Wnt-binding site of… Expand
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