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frizzled related protein-1

Known as: Secreted Apoptosis-Related Protein 2, secreted frizzled related protein-1, Secreted Frizzled-Related Protein 1 
Secreted frizzled-related protein 1 (314 aa, ~35 kDa) is encoded by the human SFRP1 gene. This protein is involved in the modulation of Wnt signaling… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
We investigated how experience regulates the structure of a defined neuronal circuit in adult mice. Enriched environment (EE… Expand
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Highly Cited
2009
Highly Cited
2009
We evaluated the healing potential of human fetal aorta–derived CD133+ progenitor cells and their conditioned medium (CD133+ CCM… Expand
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Highly Cited
2006
Highly Cited
2006
Relapses following chemotherapy are a major hindrance to patients’ survival in acute myeloid leukemia (AML). To investigate the… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE Aberrant promoter hypermethylation of Wnt-antagonist genes contributes to the pathogenesis of several cancers. We… Expand
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Highly Cited
2005
Highly Cited
2005
Mechanisms controlling human bone formation remain to be fully elucidated. We have used differential display‐polymerase chain… Expand
Highly Cited
2004
Highly Cited
2004
Previous studies have associated activation of canonical Wnt signaling in osteoblasts with elevated bone formation. Here we… Expand
Highly Cited
2004
Highly Cited
2004
We determined that sFRP‐1 mRNA was differentially expressed by osteoblast/stromal cell lines and that sFRP‐1 neutralizing… Expand
Highly Cited
2002
Highly Cited
2002
Background—The secreted frizzled related proteins (sFRP) are soluble proteins thought to interfere with the Wnt signaling. Our… Expand
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Highly Cited
2001
Highly Cited
2001
Wnt-4 signaling plays a critical role in kidney development and is associated with the epithelial conversion of the metanephric… Expand
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Highly Cited
2000
Highly Cited
2000
Secreted Frizzled-related protein-1 (sFRP-1) contains a cysteine-rich domain homologous to the putative Wnt-binding site of… Expand
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