frizzled related protein-1

Known as: Secreted Apoptosis-Related Protein 2, secreted frizzled related protein-1, Secreted Frizzled-Related Protein 1 
Secreted frizzled-related protein 1 (314 aa, ~35 kDa) is encoded by the human SFRP1 gene. This protein is involved in the modulation of Wnt signaling… (More)

Topic mentions per year

Topic mentions per year

1995-2018
051019952018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Canonical Wnt signaling has been demonstrated to increase bone formation, and Wnt pathway components are being pursued as… (More)
Is this relevant?
2008
2008
Consistent with findings of Wnt pathway members involved in vascular cells, a role for Wnt/Frizzled signaling has recently… (More)
Is this relevant?
2007
2007
Secreted Frizzled-related protein-1 (sFRP-1) belongs to a class of extracellular antagonists that modulate Wnt signaling pathways… (More)
Is this relevant?
2005
2005
Mechanisms controlling human bone formation remain to be fully elucidated. We have used differential display-polymerase chain… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Previous studies have associated activation of canonical Wnt signaling in osteoblasts with elevated bone formation. Here we… (More)
Is this relevant?
2004
2004
UNLABELLED We determined that sFRP-1 mRNA was differentially expressed by osteoblast/stromal cell lines and that sFRP-1… (More)
Is this relevant?
2002
2002
Secreted Frizzled-related protein-1 (sFRP-1), a soluble protein that binds to Wnts and modulates Wnt signaling, contains an N… (More)
Is this relevant?
2002
2002
BACKGROUND The secreted frizzled related proteins (sFRP) are soluble proteins thought to interfere with the Wnt signaling. Our… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Secreted Frizzled-related protein-1 (sFRP-1) contains a cysteine-rich domain homologous to the putative Wnt-binding site of… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Cellular resistance to multiple proapoptotic stimuli and invasion of surrounding brain tissue by migrating tumor cells are main… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?