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frizzled related protein-1

Known as: Secreted Apoptosis-Related Protein 2, secreted frizzled related protein-1, Secreted Frizzled-Related Protein 1 
Secreted frizzled-related protein 1 (314 aa, ~35 kDa) is encoded by the human SFRP1 gene. This protein is involved in the modulation of Wnt signaling… 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Compelling evidence have demonstrated that bulk tumors can arise from a unique subset of cells commonly termed “cancer stem cells… 
Highly Cited
2006
Highly Cited
2006
Relapses following chemotherapy are a major hindrance to patients’ survival in acute myeloid leukemia (AML). To investigate the… 
Highly Cited
2006
Highly Cited
2006
Purpose: We hypothesized that combined methylation analysis of Wnt antagonist genes could serve as a panel of biomarkers for… 
Highly Cited
2005
Highly Cited
2005
Mechanisms controlling human bone formation remain to be fully elucidated. We have used differential display‐polymerase chain… 
Highly Cited
2004
Highly Cited
2004
Previous studies have associated activation of canonical Wnt signaling in osteoblasts with elevated bone formation. Here we… 
Highly Cited
2004
Highly Cited
2004
We determined that sFRP‐1 mRNA was differentially expressed by osteoblast/stromal cell lines and that sFRP‐1 neutralizing… 
Highly Cited
2002
Highly Cited
2002
Background—The secreted frizzled related proteins (sFRP) are soluble proteins thought to interfere with the Wnt signaling. Our… 
Highly Cited
2001
Highly Cited
2001
Highly Cited
2000
Highly Cited
2000
Secreted Frizzled-related protein-1 (sFRP-1) contains a cysteine-rich domain homologous to the putative Wnt-binding site of…