formamidopyrimidine-DNA glycosylase

Known as: FAPY DNA Glycosylase, FAPY-DNA Glycosylase, DNA Formamidopyrimidine Glycosylase 
A DNA repair enzyme that is an N-glycosyl hydrolase with specificity for DNA-containing ring-opened N(7)-methylguanine residues.
National Institutes of Health

Papers overview

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2006
2006
The formamidopyrimidine-DNA glycosylase (Fpg) recognizes and eliminates efficiently 8-oxoguanine, an abundant mutagenic DNA… (More)
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Highly Cited
2005
Highly Cited
2005
Accurate measurement of low levels of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) in DNA is hampered by the ease with which… (More)
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2004
2004
Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidized purines such as 7,8-dihydro-8-oxoguanine… (More)
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2004
2004
Oxidative DNA damage detected by the comet assay as formamidopyrimidine DNA glycosylase (FPG) sensitive sites, almost as a rule… (More)
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Highly Cited
2004
Highly Cited
2004
DNA damage may be associated with type 2 diabetes mellitus (T2DM) and its complications mainly through oxidative stress. Little… (More)
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Highly Cited
2002
Highly Cited
2002
Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidized purines from damaged DNA. The Schiff base… (More)
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2000
2000
7,8-dihydro-8-oxoguanine (8-oxoG) and 2,6-diamino-4-hydroxyformamidopyrimidine (Fapy) are major DNA lesions formed by reactive… (More)
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1997
1997
Formamidopyrimidine-DNA glycosylase (Fpg) protein plays a prominent role in the repair of oxidatively damaged DNA in Escherichia… (More)
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Highly Cited
1997
Highly Cited
1997
Compounds of nickel(II) and cadmium(II) are carcinogenic to humans and to experimental animals. One frequently discussed… (More)
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1991
1991
We have cloned chromosomal DNA bordering an insert that inactivates mutM. Sequencing of this clone has revealed that the… (More)
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