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formamidopyrimidine-DNA glycosylase

Known as: FAPY DNA Glycosylase, FAPY-DNA Glycosylase, DNA Formamidopyrimidine Glycosylase 
A DNA repair enzyme that is an N-glycosyl hydrolase with specificity for DNA-containing ring-opened N(7)-methylguanine residues.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Within the base excision repair (BER) pathway, the DNA N-glycosylases are responsible for locating and removing the majority of… Expand
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Highly Cited
2005
Highly Cited
2005
Accurate measurement of low levels of 8‐oxo‐7,8‐dihydro‐2'‐deoxyguanosine (8‐oxodGuo) in DNA is hampered by the ease with which… Expand
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Highly Cited
2004
Highly Cited
2004
Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidized purines such as 7,8-dihydro-8-oxoguanine… Expand
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Highly Cited
2004
Highly Cited
2004
DNA damage may be associated with type 2 diabetes mellitus (T2DM) and its complications mainly through oxidative stress. Little… Expand
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Highly Cited
2002
Highly Cited
2002
Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidized purines from damaged DNA. The Schiff base… Expand
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Highly Cited
2002
Highly Cited
2002
The formamidopyrimidine‐DNA glycosylase (Fpg, MutM) is a bifunctional base excision repair enzyme (DNA glycosylase/AP lyase) that… Expand
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Highly Cited
2000
Highly Cited
2000
7,8-Dihydro-8-oxoguanine (8-oxoG) and 2,6-diamino-4-hydroxyformamidopyrimidine (Fapy) are major DNA lesions formed by reactive… Expand
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Highly Cited
1997
Highly Cited
1997
Formamidopyrimidine-DNA glycosylase (Fpg) protein plays a prominent role in the repair of oxidatively damaged DNA in Escherichia… Expand
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Highly Cited
1997
Highly Cited
1997
Compounds of nickel(II) and cadmium(II) are carcinogenic to humans and to experimental animals. One frequently discussed… Expand
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Highly Cited
1991
Highly Cited
1991
We have cloned chromosomal DNA bordering an insert that inactivates mutM. Sequencing of this clone has revealed that the… Expand
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