fontolizumab

Known as: HUZAF, Immunoglobulin G1, Anti-(Human Interferon Gamma) (Human-Mouse Monoclonal Huzaf Gamma-1-Chain), Disulfide with Human-Mouse Monoclonal Huzaf Light Chain, Dimer 
A humanized monoclonal antibody directed against interferon-gamma (IFN-g) with immunomodulatory activity. Fontolizumab binds to and prevents the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
01220042018

Papers overview

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Review
2018
Review
2018
The past three decades have witnessed remarkable advances in our ability to target specific elements of the immune and… (More)
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2010
2010
BACKGROUND The safety and efficacy of fontolizumab, a humanized anti-interferon gamma antibody, was investigated in patients with… (More)
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2008
2008
Therapeutic antibodies against tumor necrosis factor (TNF) (infliximab) and IFNgamma (fontolizumab) have been developed to treat… (More)
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2008
2008
alors appari6s avec des sujets t6moins pour des crit~res d'~ge, de sexe et de dur6e de suivi. Les patients qui avaient pr6sent6… (More)
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2006
2006
INTRODUCTION Interferon gamma is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD). We… (More)
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2006
2006
INTRODUCTION This study was designed to evaluate the safety of fontolizumab, a humanised anti-interferon gamma antibody, in… (More)
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Review
2005
Review
2005
Protein Design Labs is developing fontolizumab, a humanized anti-interferon gamma monoclonal antibody, for the potential… (More)
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Review
2005
Review
2005
Advances (from 2004 to 2006) in the use of conventional agents include the molecular mechanisms of action, which have… (More)
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2004
2004
Three-dimensional structures were determined for two crystal forms (orthorhombic P2(1)2(1)2(1) and monoclinic C2) of the Fab from… (More)
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Review
2004
Review
2004
The chimeric monoclonal antibody to tumor necrosis factor (TNF), infliximab, is an effective therapy for Crohn's disease. However… (More)
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