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fontolizumab

Known as: HUZAF, Immunoglobulin G1, Anti-(Human Interferon Gamma) (Human-Mouse Monoclonal Huzaf Gamma-1-Chain), Disulfide with Human-Mouse Monoclonal Huzaf Light Chain, Dimer 
A humanized monoclonal antibody directed against interferon-gamma (IFN-g) with immunomodulatory activity. Fontolizumab binds to and prevents the… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The past three decades have witnessed remarkable advances in our ability to target specific elements of the immune and… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The safety and efficacy of fontolizumab, a humanized anti-interferon gamma antibody, was investigated in patients with… Expand
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2008
2008
Therapeutic antibodies against tumor necrosis factor (TNF) (infliximab) and IFNgamma (fontolizumab) have been developed to treat… Expand
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Highly Cited
2006
Highly Cited
2006
INTRODUCTION Interferon gamma is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD). We… Expand
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2006
2006
Introduction: Interferon y is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD). We… Expand
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Highly Cited
2005
Highly Cited
2005
INTRODUCTION This study was designed to evaluate the safety of fontolizumab, a humanised anti-interferon gamma antibody, in… Expand
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Review
2005
Review
2005
Protein Design Labs is developing fontolizumab, a humanized anti-interferon gamma monoclonal antibody, for the potential… Expand
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Review
2005
Review
2005
Early experience of fontolizumab, a humanised anti‐interferon γ antibody, in active Crohn's disease has shown that the drug… Expand
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Review
2005
Review
2005
Advances (from 2004 to 2006) in the use of conventional agents include the molecular mechanisms of action, which have… Expand
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