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fomepizole

Known as: 4-Methylpyrazol, 1H-Pyrazole, 4-methyl-, 4-methylpyrazole 
A pyrazole with competitive alcohol dehydrogenase inhibitor activity. Fomepizole prevents the metabolism of ethylene glycol and methanol by alcohol… 
National Institutes of Health

Related topics

Related topics

10 relations
AcidosisAlcohol Dehydrogenase Inhibitors [MoA]Drug AllergyDrug toxicity

Broader (3)

AntidotePyrazolespyrazole

Narrower (1)

Antizol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Automated high throughput human CYP isoform activity assay using SPE-LC/MS method: application in CYP inhibition evaluation
1. A high throughput screening (HTS) method for the evaluation of the seven major human hepatic CYP isoform activities was… 
Highly Cited
2000
Highly Cited
2000
Acute methanol intoxication generates free radicals in rats: an ESR spin trapping investigation.
Highly Cited
1992
Highly Cited
1992
The acute effects of ethanol and acetaldehyde on rates of protein synthesis in type I and type II fibre-rich skeletal muscles of the rat.
Young rats were injected with either ethanol (75 mmol/kg), acetaldehyde (2.8 mmol/kg) or isovolumetric amounts of NaCl (0.15 mol… 
Highly Cited
1989
Highly Cited
1989
Retinoic acid synthesis by cytosol from the alcohol dehydrogenase negative deermouse.
Highly Cited
1987
Highly Cited
1987
The biosynthesis of retinoic acid from retinol by rat tissues in vitro.
Highly Cited
1986
Highly Cited
1986
Retinol metabolism in LLC-PK1 Cells. Characterization of retinoic acid synthesis by an established mammalian cell line.
Highly Cited
1984
Highly Cited
1984
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde.
Highly Cited
1978
Highly Cited
1978
Interaction of ethanol oxidation with glucuronidation in isolated hepatocytes.
Highly Cited
1973
Highly Cited
1973
The combustion of triolein-1-14C and its inhibiton by alcohol in man.
Highly Cited
1970
Highly Cited
1970
Inhibitory effect on ethanol oxidation in man after administration of 4-methylpyrazole.
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