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folate receptor

Known as: binding folate proteins 
National Institutes of Health

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Related topics

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FOLR1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Abstract 3754: Pre-clinical studies of a highly potent folate receptor targeted DNA crosslinking agent
Folate receptor (FR) targeted small molecule drug conjugates (SMDC) have shown promising results in early stage clinical trials… 
Review
2014
Review
2014
Imaging the Folate Receptor on Cancer Cells with 99mTc-Etarfolatide: Properties, Clinical Use, and Future Potential of Folate Receptor Imaging
Folate receptor (FR) can be used as a therapeutic target because of its expression on different epithelial cancers, such as… 
2014
2014
Development of a Folate Receptor (FR)-Targeted Indenoisoquinoline Using a pH-Sensitive N-Ethoxybenzylimidazole (NEBI) Bifunctional Cross-Linker
This Communication describes the synthesis and evaluation of a folate-conjugated drug delivery system (DDS) that incorporates an… 
2014
2014
EVALUATION OF ANTI-CANCER ACTIVITY OF SURVIVIN siRNA DELIVERED BY FOLATE RECEPTOR-TARGETED POLYETHYLENE-GLYCOL LIPOSOMES IN K562-BEARING XENOGRAFT MICE
Objective: To investigate anti-cancer activity of the novel survivin siRNA Folate Receptor (FR)-targeted Polyethylene-Glycol… 
2011
2011
Synthesis and evaluation of a novel lipophilic folate receptor targeting ligand.
BACKGROUND Folate receptor (FR)-targeted liposomes have been investigated as delivery vehicles for anticancer drugs. A novel… 
Highly Cited
2011
Highly Cited
2011
Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate
IntroductionFolate receptor (FR)-expressing macrophages have been shown to accumulate at sites of inflammation, where they… 
Review
2009
Review
2009
[Folate receptor-mediated antitumor drugs].
Folate receptor (FR) is over-expressed in a variety of human cancers and it is seldom expressed or found in normal tissues… 
2006
2006
Increase of doxorubicin sensitivity for folate receptor positive cells when given as the prodrug N-(phenylacetyl) doxorubicin in combination with folate-conjugated PGA.
Folate receptor (FR) has been proposed as a promising target for tumor drug targeting. The aim of this study was to increase the… 
Highly Cited
2005
Highly Cited
2005
Folate receptor specific anti-tumor activity of folate–mitomycin conjugates
Purpose: Folate receptor (FR) targeted drug conjugates were prepared by covalently attaching the vitamin folate, to the potent… 
2002
2002
Boron delivery to a murine lung carcinoma using folate receptor-targeted liposomes.
BACKGROUND Folate receptor (FR) is amplified in a variety of human tumors. Folate-derived liposomes have been shown to… 
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