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flutoprazepam

Known as: 7-chloro-1-cyclopropylmethyl-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Benzodiazepinones

Narrower (1)

KB 509
KB Cells

Papers overview

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2010
2010
Propranolol does not alter flutoprazepam kinetics and metabolism in the rat
SummaryThe influence of propranolol on the disposition of flutoprazepam, a benzodiazepine derivative extensively biotransformed… 
1996
1996
Use of Anxiolytics in Dentistry
Benzodiazepines are widely used clinically because of their antihypertensive, analgesic, anaesthetic, hypnotic properties and, in… 
1996
1996
Adsorption of psychotherapeutic drugs with various types of dialytic membranes
向精神薬を対象として透析膜への薬剤の吸着現象の解析を試み, 透析器, 濾過器によって投与量の変更が必要かを検討した.対象とした薬剤は, バルプロ酸ナトリウム (sodium valproate: SV), ゾニサミド (zonisamide: ZS… 
1990
1990
Effect of flutoprazepam on skills essential for driving motor vehicles.
The effects of the 1,4-benzodiazepine derivative flutoprazepam on the skills essential for driving motor vehicles were tested 2.5… 
1989
1989
Pharmacokinetics of flutoprazepam, a novel benzodiazepine drug, in normal subjects
SummaryThe single dose pharmacokinetics of flutoprazepam and its active N-desalkyl metabolite were determined in 8 normal… 
1986
1986
Clinical effect of Flutoprazepam (KB-509) on essential hypertension.
1984
1984
In vitro and ex vivo inhibition by flutoprazepam of [3H]flunitrazepam binding to mouse brain receptors.
The ability of flutoprazepam, a new antianxiety drug of the benzodiazepine class, to inhibit [3H]flunitrazepam binding to mouse… 
1982
1982
[Behavioral effects of flutoprazepam (KB-509) and its metabolites].
The behavioral effects of KB-509 and its metabolites were investigated and compared with those of diazepam in mice and rats. The… 
1982
1982
[Metabolic fate of flutoprazepam (KB-509). IV. Pharmacokinetics of flutoprazepam-2-14C and desalkylflutoprazepam-2-14C in dog plasma].
1981
1981
[Antiulcerogenic action of 7-chloro-1-cyclopropylmethyl-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one (KB-509), a new benzodiazepine derivative].
Effects of KB-509, a new derivative of benzodiazepines and expected to be classified as an antianxiety drug, were studied on the… 
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