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fluorapacin

Known as: bis(4-fluorobenzyl)trisulfide 
 
National Institutes of Health

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2 relations

Broader (2)

FluorobenzenesSulfides

Papers overview

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2013
2013
Metabolism of bis(4-fluorobenzyl)trisulfide and its formation of hemoglobin adduct in rat erythrocytes.
Bis(4-fluorobenzyl)trisulfide (BFBTS) is a promising new antitumor agent under investigation. It was metabolized rapidly in vivo… Expand
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2009
2009
Identification and simultaneous determination of p-FHA and p-FBA, two metabolites of anti-tumor agent--Fluorapacin in rat urine.
Fluorapacin, bis(4-fluorobenzyl)trisulfide, a small molecule natural product derivative of trisulfide, has revealed a broad… Expand
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2009
2009
Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics.
Bis(4-fluorobenzyl)trisulfide (BFBTS) is a synthetic molecule derived from a bioactive natural product, dibenzyltrisulfide, found… Expand
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2009
2009
Implications of dibenzyl trisulphide for disease treatment based on its mode of action.
Studies conducted on the secondary metabolite (natural product), dibenzyl trisulphide (DTS), which was isolated from the sub… Expand
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2008
2008
Quantitative determination of anti-tumor agent bis(4-fluorobenzyl)trisulfide, fluorapacin and its pharmaceutical preparation by high-performance liquid chromatography.
A simple isocratic and stability-indicating HPLC method was developed and validated for the quantitative determination of anti… Expand
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2008
2008
Stability studies of anticancer agent bis(4-fluorobenzyl)trisulfide and synthesis of related substances.
Bis(4-fluorobenzyl)trisulfide, fluorapacin, has been extensively developed as a promising new anticancer drug candidate. Its… Expand
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2008
2008
Crystal Structure Determination of New Antimitotic Agent Bis(p-fluorobenzyl)trisulfide
The purpose of this research was to investigate the physical characteristics and crystalline structure of bis(p-fluorobenzyl… Expand
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