flotillin-2

Known as: Epidermal Surface Antigen, Membrane Component Chromosome 17 Surface Marker 1, Flotillin 2 Protein 
Flotillin-2 (379 aa, ~42 kDa) is encoded by the human FLOT2 gene. This protein plays a role in neuronal signaling and caveolar membrane structure.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
05101519942017

Papers overview

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2010
2010
The proteins reggie-1 and reggie-2 were originally discovered in neurons during axon regeneration. Subsequently, they were… (More)
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2009
2009
Flotillin-1 and flotillin-2 co-assemble into plasma membrane microdomains that are involved in the endocytosis of molecules such… (More)
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2009
2009
Reggie-1/flotillin-2 and reggie-2/flotillin-1 are membrane raft associated proteins which have been implicated in growth factor… (More)
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Highly Cited
2008
Highly Cited
2008
The flotillins/reggie proteins are associated with noncaveolar membrane microdomains and have been implicated in the regulation… (More)
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2008
2008
The lipid-modified morphogens Wnt and Hedgehog diffuse poorly in isolation yet can spread over long distances in vivo, predicting… (More)
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Highly Cited
2007
Highly Cited
2007
Reggie-1 and -2 proteins (flotillin-2 and -1 respectively) form their own type of non-caveolar membrane microdomains, which are… (More)
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Highly Cited
2004
Highly Cited
2004
The reggie protein family consists of two proteins, reggie-1 and -2, also called flotillins, which are highly ubiquitous and… (More)
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2004
2004
Flotillin 2 (flot-2) is a highly conserved protein isolated from caveolae/lipid raft domains that tether growth factor receptors… (More)
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Highly Cited
2001
Highly Cited
2001
Lipid rafts are sphingolipid- and cholesterol-rich membrane microdomains that are insoluble in nonionic detergents, have a low… (More)
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Highly Cited
2001
Highly Cited
2001
Using confocal laser scanning and double immunogold electron microscopy, we demonstrate that reggie-1 and -2 are colocalized in… (More)
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