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flavone acetic acid
Known as:
4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-
, 4H-1-benzopyran-8-acetic Acid, 4-Oxo-2-phenyl
, FAA
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A synthetic flavonoid with vascular targeting properties. Flavone acetic acid exhibits an antiproliferative effect on endothelial cells as a result…
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National Institutes of Health
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Related topics
Related topics
7 relations
Broader (3)
Antineoplastic Agents
Flavonoids
Immunologic Adjuvants
Narrower (2)
LM 975
NSC 347512
Mitoflaxone
flavone acetic acid/interleukin-2
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
The rice bran constituent tricin potently inhibits cyclooxygenase enzymes and interferes with intestinal carcinogenesis in ApcMin mice
H. Cai
,
M. Al-Fayez
,
+4 authors
A. Gescher
Molecular Cancer Therapeutics
2005
Corpus ID: 15832423
While brown rice is a staple dietary constituent in Asia, rice consumed in the Western world is generally white, obtained from…
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Highly Cited
1995
Highly Cited
1995
Anti—vascular approaches to solid tumour therapy: Evaluation of vinblastine and flavone acetic acid
S. Hill
,
L. Sampson
,
D. Chaplin
International Journal of Cancer
1995
Corpus ID: 20952012
Several agents have now been identified which exert their anti‐tumour effects in large part via the tumour vasculature; these…
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Highly Cited
1993
Highly Cited
1993
Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.
Peter J. Worland
,
Gurmeet Kaur
,
M. Stetler-Stevenson
,
Sandra Sebers
,
Oliver Sartor
,
E A Sausville
Biochemical Pharmacology
1993
Corpus ID: 25540706
Highly Cited
1990
Highly Cited
1990
Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown.
Viswanath Mahadevan
,
Saleem T. A. Malik
,
A. Meager
,
Walter Fiers
,
Graham P. Lewis
,
Ian R. Hart
Cancer Research
1990
Corpus ID: 17036027
Flavone acetic acid (FAA), a novel investigational antitumor agent, has been shown to cause early vascular shutdown in several…
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Highly Cited
1989
Highly Cited
1989
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.
L. Zwi
,
Bruce C. Baguley
,
John B. Gavin
,
William R. Wilson
Journal of the National Cancer Institute
1989
Corpus ID: 24230950
Some investigators have suggested that the marked activity of flavone acetic acid (FAA) against advanced solid tumors in mice…
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Highly Cited
1989
Highly Cited
1989
Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.
Mike C. Bibby
,
J. Double
,
P. Loadman
,
C. Duke
Journal of the National Cancer Institute
1989
Corpus ID: 36676746
Flavone acetic acid (FAA) is active against normally refractory murine sc tumors. Clinical studies are disappointing despite…
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Highly Cited
1988
Highly Cited
1988
Flavone acetic acid (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy.
J. Evelhoch
,
M. Bissery
,
+4 authors
T. Corbett
Cancer Research
1988
Corpus ID: 16310373
Flavone acetic acid (FAA), a new drug with broad activity against transplanted solid tumors of mice, induces nonrepairable DNA…
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Highly Cited
1987
Highly Cited
1987
Phase I and pharmacokinetic study of flavone acetic acid.
D. Kerr
,
S. Kaye
,
+7 authors
M. Soukop
Cancer Research
1987
Corpus ID: 25784227
Flavone acetic acid is the second in a series of compounds based on the flavonoid aglycone ring structure to be clinically…
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Highly Cited
1986
Highly Cited
1986
Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice.
J. Plowman
,
V. Narayanan
,
+4 authors
K. Paull
Cancer treatment reports
1986
Corpus ID: 19109262
Flavone acetic acid, given on Days 2 and 9 at a dose of 267 mg/kg, inhibited tumor growth completely in 60%-80% of mice with…
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Highly Cited
1972
Highly Cited
1972
Effect of Ethylene on Cell Division and Deoxyribonucleic Acid Synthesis in Pisum sativum.
A. Apelbaum
,
S. P. Burg
Plant Physiology
1972
Corpus ID: 20956314
Ethylene and supraoptimal levels of 2,4-dichlorophenoxyacetic acid inhibit the growth of the apical hook region of etiolated…
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