flavone acetic acid

Known as: 4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-, 4H-1-benzopyran-8-acetic Acid, 4-Oxo-2-phenyl, FAA 
A synthetic flavonoid with vascular targeting properties. Flavone acetic acid exhibits an antiproliferative effect on endothelial cells as a result… (More)
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Antineoplastic AgentsFlavonoidsImmunologic Adjuvants

Narrower (2)

LM 975NSC 347512
flavone acetic acid/interleukin-2

Papers overview

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Highly Cited
2011
Highly Cited
2011
Habitual intake of flavonoid subclasses and incident hypertension in adults.
BACKGROUND Dietary flavonoids have beneficial effects on blood pressure in intervention settings, but there is limited… (More)
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Highly Cited
2002
Highly Cited
2002
Antiproliferative activities of citrus flavonoids against six human cancer cell lines.
Citrus fruits contain high concentrations of several classes of phenols, including numerous hydroxycinnamates, flavonoid… (More)
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Highly Cited
1996
Highly Cited
1996
Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
Flavopiridol (L86-8275), a N-methylpiperidinyl, chlorophenyl flavone, can inhibit cell cycle progression in either G1 or G2 and… (More)
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Highly Cited
1992
Highly Cited
1992
Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275.
BACKGROUND Previous studies have shown that polyhydroxylated flavonoids such as quercetin and genistein can inhibit tumor cell… (More)
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1989
1989
Flavone acetic acid induces a coagulopathy in mice.
The effects of flavone acetic acid (FAA) on the coagulation properties of plasma from tumour-bearing and non-tumour-bearing mice… (More)
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Highly Cited
1989
Highly Cited
1989
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.
Some investigators have suggested that the marked activity of flavone acetic acid (FAA) against advanced solid tumors in mice… (More)
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1987
1987
Phase I and pharmacokinetic study of flavone acetic acid.
Flavone acetic acid is the second in a series of compounds based on the flavonoid aglycone ring structure to be clinically… (More)
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1987
1987
Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid).
LM985 has been shown previously to hydrolyse to flavone acetic acid (LM975) in mouse plasma and to produce significant anti… (More)
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Highly Cited
1986
Highly Cited
1986
Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice.
Flavone acetic acid, given on Days 2 and 9 at a dose of 267 mg/kg, inhibited tumor growth completely in 60%-80% of mice with… (More)
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1986
1986
Activity of flavone acetic acid (NSC-347512) against solid tumors of mice
Flavone acetic acid (FAA) is a new antitumor agent that has recently entered Phase I clinical trials. In preclinical studies, we… (More)
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