fexofenadine

Known as: Terfenadine carboxylate, Carboxyterfenadine, fexofenadine [Chemical/Ingredient] 
A second generation, long-lasting selective histamine H1 receptor antagonist with antiinflammatory property. Fexofenadine is a highly selective and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
020406019962018

Papers overview

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2008
2008
Fexofenadine (FEX) is mainly eliminated from the liver into bile in unchanged form. We demonstrated previously that organic anion… (More)
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Highly Cited
2007
Highly Cited
2007
The goals of this study were to assess the extent of human intestinal drug transporter expression, determine the subcellular… (More)
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2004
2004
Purpose. To investigate the membrane transport mechanisms of fexofenadine in the Caco-2 model. Methods. Transport studies were… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES Our objective was to examine the effect of different fruits and their constituents on P-glycoprotein and organic anion… (More)
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2002
2002
BACKGROUND St John's wort is a popular over-the-counter dietary supplement and herbal remedy that has been implicated in drug… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE Our objective was to assess the effect of rifampin (INN, rifampicin) on the pharmacokinetics of fexofenadine and to… (More)
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Highly Cited
2001
Highly Cited
2001
MDR1 (P-glycoprotein) is an important factor in the disposition of many drugs, and the involved processes often exhibit… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Sedating antihistamines may impair driving performance as seriously as alcohol. OBJECTIVE To compare the effects of… (More)
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Highly Cited
1999
Highly Cited
1999
Fexofenadine, a nonsedating antihistamine, does not undergo significant metabolic biotransformation. Accordingly, it was… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Administration of the antihistamine terfenadine (Seldane) to patients may result in acquired long QT syndrome and… (More)
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