Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

felbamate

Known as: 2-Phenyl-1,3-propanediol dicarbamate, Felbamatum, Carbamic Acid, 2-phenyltrimethylene Ester 
A propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Background: Antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment. Since 1989, 18 new AEDs have been licensed for… Expand
Is this relevant?
Review
2005
Review
2005
Gamma-aminobutyric acid (GABA), one of the main inhibitory neurotransmitters in the brain, interacts with three types of… Expand
  • table 1
  • table 2
  • table 3
Is this relevant?
Review
2004
Review
2004
Antiepileptic drugs (AEDs) provide satisfactory control of seizures for most patients with epilepsy. The drugs have the… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Although a series of new antiepileptic drugs (AEDs) have been launched in the last two decades, drug-refractoriness remains a… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Felbamate is a promising new antiepileptic drug whose mechanism of action is unknown. In whole‐cell voltage clamp recordings from… Expand
Is this relevant?
Highly Cited
1993
Highly Cited
1993
BACKGROUND The Lennox-Gastaut syndrome is a childhood disorder characterized by multiple types of seizures, mental retardation… Expand
Is this relevant?
Highly Cited
1993
Highly Cited
1993
We evaluated felbamate (FBM) monotherapy in 111 patients with uncontrolled partial-onset seizures in a multicenter, double-blind… Expand
  • table 1
  • table 2
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Felbamate (FBM) monotherapy was evaluated in 44 patients with uncontrolled partial onset seizures in a unique, single‐center… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Felbamate (2-phenyl-1,3-propanediol dicarbamate) has a favorable preclinical profile in animal models of epilepsy. We present the… Expand
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Summary: Felbamate (2‐phenyl‐1, 3‐propanediol dicarbamate), phenytoin, phenobarbital, ethosuximide, and valproate were evaluated… Expand
Is this relevant?