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febuxostat
Known as:
2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid
, Febuxostatum
, 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic Acid
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An orally available, non-purine inhibitor of xanthine oxidase with uric acid lowering activity. Upon oral administration, febuxostat selectively and…
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National Institutes of Health
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Related topics
Related topics
14 relations
Broader (1)
Gout Suppressants
In Blood
NCIt Antineoplastic Agent Terminology
Xanthine Oxidase Inhibitors [MoA]
agonists
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Narrower (2)
TEI 6720
Uloric
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Cardiovascular safety of febuxostat and allopurinol
Drug and therapeutics bulletin
2018
Corpus ID: 49432093
The authors of a randomised controlled study have reported that secondary outcome measures of all-cause mortality and…
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2016
2016
Estimation of Febuxostat drug present in formulation by RP-HPLC
A. Gunda
,
N. Aravindsai
,
K. Reddy
,
Anand Kumar
2016
Corpus ID: 212546685
A novel reverse phase liquid chromatographic technique was developed for the analysis of Febuxostat. Developed method was simple…
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Review
2015
Review
2015
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING METHOD FOR SIMULTANEOUS ESTIMATION OF FEBUXOSTAT AND DICLOFENAC POTASSIUM IN BULK AND TABLET DOSAGE FORM USING RP-HPLC
Uttam Prasad Panigrahy
,
A. Reddy
2015
Corpus ID: 212587411
A novel method for the simultaneous estimation of Febuxostat and Diclofenac Potassium in combine dosage form was developed and…
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2014
2014
FORMULATION AND EVALUATION OF FEBUXOSTAT FAST DISINTEGRATING TABLET
R. Dass
,
Sandhya Jaiswal
,
G. Gupta
2014
Corpus ID: 55980023
Article history Gout is a metabolic disorder characterized by elevated uric acid levels in the body, associated with painful…
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2013
2013
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF FEBUXOSTAT AND KETOROLAC IN TABLET DOSAGE FORMS BY RP-HPLC
B. Raja
,
A. Rao
2013
Corpus ID: 98744694
A simple, accurate, precise and rapid reversed-phase high performance liquid chromatographic (RP-HPLC) method has been developed…
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2013
2013
Development and Validation of Zero and First Order Derivative UV-Spectrophotometric Method for Determination of Febuxostat in Bulk and in Formulation
Ch. Rajyalakshmi
,
T. Benjamin
,
C. R. Babu
2013
Corpus ID: 123520098
Two simple, sensitive, precise and economical UV-spectrophotometric methods have been developed for the determination of…
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2012
2012
The gout pipeline crystallizes
J. Kotz
Nature reviews. Drug discovery
2012
Corpus ID: 30631999
The gout space is heating up, but is there sufficient room in the market to accommodate multiple new therapeutics?
2011
2011
Determination of the contents of febuxostat in human plasma by HPLC-FLU and studies on its pharmacokinetics
Guo-ping Yang
2011
Corpus ID: 101970520
AIM:To study the pharmacokinetics of febuxostat tablets and establish an HPLC method for determining the contents of the…
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2010
2010
Febuxostat (Uloric) for Hyperuricemia and Gout
B. Love
2010
Corpus ID: 58140935
Febuxostat more effectively lowers serum uric acid to goal levels than does allopurinol; however, this benefit is offset by a…
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2009
2009
Febuxostat: new drug. Hyperuricaemia: risk of gout attacks.
Prescrire international
2009
Corpus ID: 29750223
(1) For patients with chronic symptomatic hyperuricaemia who fail to respond to a low purine diet, allopurinol is the standard…
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