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fatty acid deficiency

National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Omega-3 fatty acid deficiency increases constitutive pro-inflammatory cytokine production in rats: relationship with central serotonin turnover.
Omega-3 (n-3) fatty acid deficiency, elevated inflammatory signaling, and central serotonin (5-HT) turnover have separately been… Expand
Highly Cited
2006
Highly Cited
2006
Maternal dietary (n-3) fatty acid deficiency alters neurogenesis in the embryonic rat brain.
Docosahexaenoic acid [22:6(n-3)] is enriched in brain membrane phospholipids and essential for brain function. Neurogenesis… Expand
Highly Cited
2004
Highly Cited
2004
Essential fatty acids and phospholipase A2 in autistic spectrum disorders.
A health questionnaire based on parental observations of clinical signs of fatty acid deficiency (FAD) showed that patients with… Expand
Review
2003
Review
2003
Problems with essential fatty acids: time for a new paradigm?
  • S. Cunnane
  • Progress in lipid research
  • 2003
    • Corpus ID: 31301489
The term 'essential fatty acid' is ambiguous and inappropriately inclusive or exclusive of many polyunsaturated fatty acids. When… Expand
Highly Cited
2002
Highly Cited
2002
A randomized double-blind, placebo-controlled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specific learning difficulties
(1) The authors tested the prediction that relative deficiencies in highly unsaturated fatty acids (HUFAs) may underlie some of… Expand
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Review
2001
Review
2001
Essential fatty acids in visual and brain development
Essential fatty acids are structural components of all tissues and are indispensable for cell membrane synthesis; the brain… Expand
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Highly Cited
1995
Highly Cited
1995
Patients with anorexia nervosa demonstrate deficiencies of selected essential fatty acids, compensatory changes in nonessential fatty acids and decreased fluidity of plasma lipids.
The objective of this study was to assess the essential fatty acid status of patients with anorexia nervosa. Blood was collected… Expand
Highly Cited
1990
Highly Cited
1990
Dietary effects on brain fatty acid composition: the reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain, erythrocytes, and plasma of rhesus monkeys.
Rhesus monkeys given pre- and postnatal diets deficient in n-3 essential fatty acids develop low levels of docosahexaenoic acid… Expand
Highly Cited
1981
Highly Cited
1981
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.
Prostaglandins and related compounds are active mediators of inflammation, but data concerning their role in the pathogenesis of… Expand
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Highly Cited
1980
Highly Cited
1980
The permeability barrier in essential fatty acid deficiency: evidence for a direct role for linoleic acid in barrier function.
Essential fatty acid (EFA) deficient rodents demonstrate abnormal epidermal permeability barrier function and differentiation… Expand
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