fast axonal transport

Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc… (More)

The giant axon of the squid provides a unique cell biological model for analyzing the biochemistry and cell biology of the axon… (More)

We have developed a model that accounts for the effect of a non-uniform distribution of tau protein along the axon length on fast… (More)

Alzheimer's disease (AD) and other tauopathies are characterized by fibrillar inclusions composed of the microtubule-associated… (More)

The pathological mechanism by which Abeta causes neuronal dysfunction and death remains largely unknown. Deficiencies in fast… (More)

Selected vulnerability of neurons in Huntington's disease suggests that alterations occur in a cellular process that is… (More)

Expansion of the polyglutamine (polyQ) stretch in the androgen receptor (AR) protein leads to spinal and bulbar muscular atrophy… (More)