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Fast axonal transport (FAT) requires consistent energy over long distances to fuel the molecular motors that transport vesicles… Expand Alzheimer's disease (AD) is characterized by progressive, age-dependent degeneration of neurons in the central nervous system. A… Expand Alzheimer's disease (AD) and other tauopathies are characterized by fibrillar inclusions composed of the microtubule-associated… Expand Aggregated filamentous forms of hyperphosphorylated tau (a microtubule-associated protein) represent pathological hallmarks of… Expand The neuropathology of Alzheimer's disease (AD) and other tauopathies is characterized by filamentous deposits of the microtubule… Expand Selected vulnerability of neurons in Huntington's disease suggests that alterations occur in a cellular process that is… Expand The pathological mechanism by which Aβ causes neuronal dysfunction and death remains largely unknown. Deficiencies in fast axonal… Expand The pathological mechanism by which Abeta causes neuronal dysfunction and death remains largely unknown. Deficiencies in fast… Expand Amyotrophic lateral sclerosis (ALS) is a late-onset neurological disorder characterized by death of motoneurons. Mutations in Cu… Expand Expansion of the polyglutamine (polyQ) stretch in the androgen receptor (AR) protein leads to spinal and bulbar muscular atrophy… Expand