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fMet-Leu-Phe receptor

Known as: N Formylmethionyl Peptide Receptor, N formyl Hexapeptide Receptor, F Chemotactic Peptide Receptor 
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL… 
National Institutes of Health

Related topics

Related topics

9 relations
FPR1 geneIn Bloodagonistsantagonists & inhibitors

Narrower (3)

FPR1 protein, humanFPR2 protein, humanFpr-rs8 protein, mouse

Papers overview

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Highly Cited
1986
Highly Cited
1986
The role of polyphosphoinositides and their breakdown products in A23187-induced release of arachidonic acid from rabbit polymorphonuclear leucocytes.
Stimulation of rabbit polymorphonuclear leucocytes with A23187 causes phospholipase C mediated breakdown of polyphosphoinositides… 
1986
1986
Characterization of the plasma membrane bound GTPase from rabbit neutrophils. I. Evidence for an Ni-like protein coupled to the formyl peptide, C5a, and leukotriene B4 chemotaxis receptors.
We have characterized the GTPase activity of the Ni-like guanine-nucleotide-binding regulatory protein in rabbit neutrophil… 
Highly Cited
1985
Highly Cited
1985
Inositol phosphate formation in fMet-Leu-Phe-stimulated human neutrophils does not require an increase in the cytosolic free Ca2+ concentration.
The accumulation of inositol phosphates in myo-[3H]inositol-labelled human neutrophils stimulated with the chemotactic peptide… 
Highly Cited
1984
Highly Cited
1984
Cyclic AMP inhibition of fMet-Leu-Phe-dependent metabolic responses in human neutrophils is not due to its effects on cytosolic Ca2+.
Cyclic AMP powerfully inhibits the fMet-Leu-Phe-dependent respiratory burst and exocytosis of azurophilic and specific granules… 
1984
1984
Mobilization and adaptation of human neutrophil chemoattractant fMet-Leu-Phe receptors.
Neutrophil responsiveness to N-formylmethionylleucylphenylalanine (fMet-Leu-Phe) appears to involve either receptor recycling and… 
1984
1984
Neutrophil chemoattractant fMet-Leu-Phe receptor expression and ionic events following activation.
The identification of receptors for chemotactic factors on neutrophils opened a new era in the investigation of these cells. The… 
Highly Cited
1983
Highly Cited
1983
Crawling-like movements, adhesion to solid substrata and chemokinesis of neutrophil granulocytes.
We analysed the chemokinetic actions of fMet-Leu-Phe (FMLP) and human serum albumin (HSA) on preparations of human neutrophils… 
1981
1981
A monoclonal antibody inhibiting human neutrophil chemotaxis and degranulation.
The hybridoma technique of Kohler and Milstein was used to raise a monoclonal antibody against human neutrophils it has been… 
1979
1979
Synthetic peptide chemotactic factors for neutrophils: the range of active peptides, their efficacy and inhibitory activity, and susceptibility of the cellular response to enzymes and bacterial…
The chemotactic activity for neutrophil leucocytes of twenty-six peptides of varied sequence, of which the majority were N… 
Highly Cited
1976
Highly Cited
1976
Histamine release by chemotactic, formyl methionine-containing peptides.
Certain formyl dipeptides and tripeptides containing methionine released histamine from human basophils at concentrations of 10…