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ezetimibe

Known as: Ezetimiba, (1-(4-fluorophenyl)-(3R)-(3-(4-fluorophenyl)-(3S)-hydroxypropyl)-(4S)-(4-hydroxyphenyl)-2-azetidinone), Ezetimibe [Chemical/Ingredient] 
An azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Summary Background After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction… Expand
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Review
2018
Review
2018
The 2013 ACC/AHA guidelines on blood cholesterol management were a major shift in the delineation of the main patient groups that… Expand
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Review
2017
Review
2017
Recent years have brought a significant amount of new results in the field of atherosclerosis. A better understanding of the role… Expand
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Highly Cited
2015
Highly Cited
2015
RESULTS The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in… Expand
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Highly Cited
2011
Highly Cited
2011
Summary Background Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and… Expand
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Highly Cited
2011
Highly Cited
2011
Cardiovascular disease (CVD) due to atherosclerosis of the arterial vessel wall and to thrombosis is the foremost cause of… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Treatment added to statin monotherapy to further modify the lipid profile may include combination therapy to either… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density lipoprotein (LDL) cholesterol when added… Expand
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Highly Cited
2007
Highly Cited
2007
Niemann-Pick C1-like 1 (NPC1L1) is required for cholesterol absorption. Intestinal NPC1L1 appears to be a target of ezetimibe, a… Expand
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Highly Cited
2002
Highly Cited
2002
Background—Ezetimibe has been shown to inhibit cholesterol absorption in animal models, but studies on cholesterol absorption in… Expand
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