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ezetimibe / Simvastatin

Known as: Butanoic Acid, 2,2-Dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl Ester, Mixture with (3R,4S)-1-(4-Fluorophenyl)-3-((3S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-2-azetidinone, Ezetimibe-Simvastatin Combination, Ezetimibe, Simvastatin Drug Combination 
An orally bioavailable combination agent containing the cholesterol absorption inhibitor ezetimibe and the hepatic hydroxymethyl-glutaryl coenzyme A… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Immunotherapies are the most rapidly growing drug class and have a major impact in oncology and on human health. It is… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Hyperlipidemia has been suggested as a risk factor for stenosis of the aortic valve, but lipid-lowering studies have… Expand
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Highly Cited
2006
Highly Cited
2006
CONTEXT Carotid artery intima-media thickness (CIMT) is a marker of coronary atherosclerosis and independently predicts… Expand
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Highly Cited
2005
Highly Cited
2005
Ezetimibe is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia, but… Expand
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Highly Cited
2004
Highly Cited
2004
CONTEXT Although chronic Helicobacter pylori infection is associated with gastric cancer, the effect of H pylori treatment on… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Entecavir (ETV) exhibits potent antiviral activity in patients chronically infected with wild-type or lamivudine (3TC… Expand
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Highly Cited
2003
Highly Cited
2003
Background—Despite the established efficacy of statins, many patients do not achieve recommended LDL cholesterol (LDL-C) goals… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES The purpose of this study was to assess the efficacy and safety of ezetimibe administered with simvastatin in patients… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Hormone replacement therapy (HRT) given as unopposed estrogen replacement therapy (ERT) gained widespread popularity… Expand
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